期刊
RHEUMATOLOGY
卷 50, 期 3, 页码 450-462出版社
OXFORD UNIV PRESS
DOI: 10.1093/rheumatology/keq266
关键词
Rheumatoid arthritis; Obesity; Body composition; Body fat; Cachexia; Physical activity; Diet; Lifestyle; Smoking cessation
类别
资金
- Dudley Group of Hospitals
- Wolverhampton University
- Arthritis Research Campaign [17682]
Obesity is a major threat for public health and its study has attracted significant attention in the general population, predominantly due to its association with significant metabolic and cardiovascular complications. In RA research, BMI is frequently reported as a demographical variable, but obesity, as such, has received little interest. This is surprising, in view of the clear associations of obesity with other arthritides, particularly OA, but also in view of the now-clear association of RA with increased cardiovascular morbidity and mortality. In this review, we summarize the studies that have looked into obesity in the RA population, evaluate their findings, identify knowledge gaps and propose directions for future research. We also pose a question of high clinical and research significance: is the use of BMI still a valid way of assessing obesity in RA?.
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