期刊
RHEUMATOLOGY
卷 48, 期 11, 页码 1392-1397出版社
OXFORD UNIV PRESS
DOI: 10.1093/rheumatology/kep266
关键词
Systemic lupus erythematosus; Immigration; Hispanics; Mexicans
类别
资金
- National Institute of Arthritis and Musculoskeletal and Skin Diseases [P01 AR49084]
- General Clinical Research Center [M01-RR02558, M01-RR00032]
- Mary Kirkland Scholars program
- Rheuminations, Inc. (UAB)
Objective. To compare the socio-economic characteristics, clinical features and health-related quality of life in Hispanic SLE patients residing in Mexico and in the Southwest USA (Mexican and Texan, herein). Methods. Mexican and Texan SLE patients (fulfilling ACR criteria) participating in separate longitudinal outcome studies were evaluated. Texan patients were randomly chosen to match total disease duration with the Mexican patients. Cross-sectional data for the Mexican patients were obtained by a US-trained investigator who had previously participated in data collection for the cohort to which the Texan patients belonged. Socio-economic and -demographic characteristics, clinical characteristics, disease activity (with SLAM-Revised), damage accrual (with SLICC/ACR Damage Index) and self-reported function (with Short Form-36) were compared between the two groups. Results. Seventy Mexican patients were matched with either one or two Texan patients (n=94) for a total of 164 patients. Mexican patients were younger. In age-adjusted analyses, the Mexican patients were more educated, had better health-related quality of life and overall less systemic SLE manifestations. Mexican patients were exposed more frequently to AZA. Conclusions. Texan patients had more severe disease than the Mexican patients. In multivariable analyses, Texan Hispanic ethnicity was significantly associated with high disease activity, but significance was not reached for damage. The discrepant findings observed between these two Hispanic groups of SLE patients may reflect socio-economic or biological factors. Given the global phenomenon of immigration, rheumatologists should be aware of the overall course and outcome of immigrant SLE patients if undesirable outcomes are to be prevented.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据