期刊
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
卷 40, 期 2, 页码 251-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.rdc.2014.01.005
关键词
Crystal arthropathies; Comorbidities; Gout; Hyperuricemia; Cardiovascular disease; Metabolic syndrome; Renal disease; Calcium pyrophosphate arthropathy
类别
资金
- Savient
- Takeda
- Regeneron
- Allergan
- Agency for Health Quality and Research Center for Education and Research on Therapeutics (CERTs)
- National Institute of Arthritis, Musculoskeletal and Skin Diseases (NIAMS)
- National-Institute of Aging (NIA)
- National Cancer Institute (NCI)
- Birmingham VA Medical Center
Crystal arthropathies are among the most common causes of painful inflammatory arthritis. Gout, the most common example, has been associated with cardiovascular and renal disease. In recent years, evidence for these associations and those involving other comorbidities, such as the metabolic syndrome, have emerged, and the importance of asymptomatic hyperuricemia has been established. In this review, an update on evidence, both experimental and clinical, is presented, and associations between hyperuricemia, gout, and several comorbidities are described.. Causality regarding calcium pyrophosphate arthropathy and associated comorbidities is also reviewed.
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