Risk factors for physical disability at diagnosis of 19,283 new cases of leprosy

Introduction: The purpose of this study was to evaluate risk factors for physical disability at the moment of leprosy diagnosis. Methods: This is a retrospective, descriptive and exploratory investigation of 19,283 patients with leprosy, registered in the State of Minas Gerais, Brazil, between 2000 and 2005. Results: The risk of Grade 2 disability was 16.5-fold higher in patients with lepromatous leprosy, and 12.8-fold higher in patients presenting the borderline form, compared to patients presenting indeterminate leprosy. The occurrence of more than one thickened nerve increased the odds of a patient developing Grade 2 disability, 8.4-fold. Age < 15 years, multibacillary leprosy and no formal education presented 7.0, 5.7 and 5.6 odds of developing physical disability, respectively. Conclusions: These factors should be considered as strong prognostic indicators in the development of physical disability at diagnosis.