期刊
REVISTA DA ASSOCIACAO MEDICA BRASILEIRA
卷 58, 期 4, 页码 493-497出版社
ASSOC MEDICA BRASILEIRA
DOI: 10.1590/S0104-42302012000400023
关键词
Sexual steroids; bone; hyaline cartilage; osteoarthritis
In Brazil, the increase in the reported cases of degenerative diseases of articular cartilage is 20% per year, meaning that 200,000 Brazilians develop degenerative joint diseases every year, which have a negative impact on bone mass. This study shows evidence that hormone production of sexual steroids (estrogens, progestogens, and androgens) have an influence on cartilage quality, as well as on bone mass. Therefore, this review aimed to analyze literature data on the molecular and genic action of sexual steroids on hyaline cartilage and bone physiology, as well as osteoarthritis interference on the quality of these structures.
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