期刊
NATURE STRUCTURAL & MOLECULAR BIOLOGY
卷 22, 期 4, 页码 342-U93出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nsmb.2992
关键词
-
资金
- US National Center for Research Resources at the US National Institutes of Health [GM103403]
- US National Institutes of Health [GM022778, GM022854]
We report crystal structures of the Thermus thermophilus ribosome at 2.3- to 2.5-angstrom resolution, which have enabled modeling of rRNA modifications. The structures reveal contacts of modified nucleotides with mRNA and tRNAs or protein pY, and contacts within the ribosome interior stabilizing the functional fold of rRNA. Our work provides a resource to explore the roles of rRNA modifications and yields a more comprehensive atomic model of a bacterial ribosome.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据