期刊
REVIEWS IN FISH BIOLOGY AND FISHERIES
卷 20, 期 3, 页码 435-439出版社
SPRINGER
DOI: 10.1007/s11160-009-9133-2
关键词
Aeromonas hydrophila; Beta-glucan; Defence mechanisms; Tinca tinca
Influence of beta-1.3/1.6-glucan (Macrogard) on the innate immunity and protection against Aeromonas hydrophila in tench (Tinca tinca (L.)) was assessed. Macrogard was fed at doses of 0, 0.5, 1 and 2 g kg(-1) of pellets for 1 month. The blood, spleen and head kidney from 10 fish of each group were separated and analysed for immunity parameters. Twenty tench from each group were infected with A. hydrophila. Macrogard at doses 1 and 2 g kg(-1) of feed significantly (P < 0.05) increased the phagocytic activity of macrophages and proliferative response of mitogens stimulated lymphocytes. The same doses significantly (P < 0.05) increased lysozyme activity and Ig level in serum, compared to the control and dose 0.5 g kg(-1) of feed. The challenge test showed that Macrogard reduced mortality of tench after experimental infection (5-35%).
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