期刊
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS
卷 13, 期 4, 页码 253-263出版社
SPRINGER
DOI: 10.1007/s11154-012-9228-2
关键词
Progesterone; Estradiol; Androgen; Glucocorticoid; Hypoxia; Inflammation
资金
- Wellcome Trust [083908/Z/07/Z]
- Medical Research Council [G0600048]
- Wellcome Trust [083908/Z/07/Z] Funding Source: Wellcome Trust
- Medical Research Council [G0600048, G1002033] Funding Source: researchfish
- MRC [G0600048, G1002033] Funding Source: UKRI
The ovarian steroid hormones progesterone and estradiol are well established regulators of human endometrial function. However, more recent evidence suggests that androgens and locally generated steroids, such as the glucocorticoids, also have a significant impact on endometrial breakdown and repair. The temporal and spatial pattern of steroid receptor presence in endometrial cells has a significant impact on the endometrial response to steroids. Furthermore, regulation of steroid receptor function by modulatory proteins further refines local responses. This review focuses on steroid regulation of endometrial function during the luteo-follicular transition with a focus on menstruation and endometrial repair.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据