期刊
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS
卷 9, 期 2, 页码 161-170出版社
SPRINGER
DOI: 10.1007/s11154-007-9072-y
关键词
vitamin D; rickets; epidemiology; infants; children; adolescents
资金
- NICHD NIH HHS [R01 HD43869, R01 HD043869] Funding Source: Medline
- PHS HHS [5-T71-MC-00009-14] Funding Source: Medline
Vitamin D deficiency is highly prevalent among children and adolescents worldwide. The high rates of vitamin D deficiency during childhood are of major public health relevance, given the growing evidence that vitamin D deficiency may play a key role in the pathophysiology of many chronic diseases beyond rickets, including autoimmune conditions, cardiovascular diseases, and cancer. Identification, treatment, and prevention of vitamin D deficiency in childhood may therefore have profound health effects throughout the life span. In this review, we discuss the definitions, epidemiology, clinical implications, and treatment of vitamin D deficiency in children and adolescents.
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