相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Human Antibodies that Neutralize HIV-1: Identification, Structures, and B Cell Ontogenies
Peter D. Kwong et al.
IMMUNITY (2012)
Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies from an HIV-1 Vaccine Efficacy Trial Target Multiple Epitopes and Preferentially Use the VH1 Gene Family
Mattia Bonsignori et al.
JOURNAL OF VIROLOGY (2012)
Increased HIV-1 vaccine efficacy against viruses with genetic signatures in Env V2
Morgane Rolland et al.
NATURE (2012)
Targeting Antibody Responses to the Membrane Proximal External Region of the Envelope Glycoprotein of Human Immunodeficiency Virus
Donatien Kamdem Toukam et al.
PLOS ONE (2012)
Structure-guided Alterations of the gp41-directed HIV-1 Broadly Neutralizing Antibody 2F5 Reveal New Properties Regarding its Neutralizing Function
Javier Guenaga et al.
PLOS PATHOGENS (2012)
Structural Mechanism of Trimeric HIV-1 Envelope Glycoprotein Activation
Erin E. H. Tran et al.
PLOS PATHOGENS (2012)
Cell-to-Cell Transfer of HIV-1 via Virological Synapses Leads to Endosomal Virion Maturation that Activates Viral Membrane Fusion
Benjamin M. Dale et al.
CELL HOST & MICROBE (2011)
Antibody Response to Polyhistidine-Tagged Peptide and Protein Antigens Attached to Liposomes via Lipid-Linked Nitrilotriacetic Acid in Mice
Douglas S. Watson et al.
CLINICAL AND VACCINE IMMUNOLOGY (2011)
Targeting HIV-1 gp41 in Close Proximity to the Membrane Using Antibody and Other Molecules
Johannes S. Gach et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2011)
Role for the Terminal Clasp of HIV-1 gp41 Glycoprotein in the Initiation of Membrane Fusion
Chan-Sien Lay et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
HIV-1 Envelope Glycoprotein Biosynthesis, Trafficking, and Incorporation
Mary Ann Checkley et al.
JOURNAL OF MOLECULAR BIOLOGY (2011)
The V1V2 Domain and an N-Linked Glycosylation Site in the V3 Loop of the HIV-1 Envelope Glycoprotein Modulate Neutralization Sensitivity to the Human Broadly Neutralizing Antibody 2G12
Antoine Chaillon et al.
JOURNAL OF VIROLOGY (2011)
Direct Antibody Access to the HIV-1 Membrane-Proximal External Region Positively Correlates with Neutralization Sensitivity
B. K. Chakrabarti et al.
JOURNAL OF VIROLOGY (2011)
Selection with a Peptide Fusion Inhibitor Corresponding to the First Heptad Repeat of HIV-1 gp41 Identifies Two Genetic Pathways Conferring Cross-Resistance to Peptide Fusion Inhibitors Corresponding to the First and Second Heptad Repeats (HR1 and HR2) of gp41
Wei Wang et al.
JOURNAL OF VIROLOGY (2011)
Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing
Xueling Wu et al.
SCIENCE (2011)
Maturation-Induced Cloaking of Neutralization Epitopes on HIV-1 Particles
Amanda S. Joyner et al.
PLOS PATHOGENS (2011)
Role for the disulfide-bonded region of human immunodeficiency virus type 1 gp41 in receptor-triggered activation of membrane fusion function
Anna K. Bellamy-McIntyre et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Virological Synapse-Mediated Spread of Human Immunodeficiency Virus Type 1 between T Cells Is Sensitive to Entry Inhibition
Nicola Martin et al.
JOURNAL OF VIROLOGY (2010)
Variable Loop Glycan Dependency of the Broad and Potent HIV-1-Neutralizing Antibodies PG9 and PG16
Katie J. Doores et al.
JOURNAL OF VIROLOGY (2010)
Topological Layers in the HIV-1 gp120 Inner Domain Regulate gp41 Interaction and CD4-Triggered Conformational Transitions
Andres Finzi et al.
MOLECULAR CELL (2010)
Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility
Marie Pancera et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Elicitation of structure-specific antibodies by epitope scaffolds
Gilad Ofek et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Crystal Structure of HIV-1 gp41 Including Both Fusion Peptide and Membrane Proximal External Regions
Victor Buzon et al.
PLOS PATHOGENS (2010)
Molecular Architectures of Trimeric SIV and HIV-1 Envelope Glycoproteins on Intact Viruses: Strain-Dependent Variation in Quaternary Structure
Tommi A. White et al.
PLOS PATHOGENS (2010)
Neutralizing antibodies induced by liposomal HIV-1 glycoprotein 41 peptide simultaneously bind to both the 2F5 or 4E10 epitope and lipid epitopes
Gary R. Matyas et al.
AIDS (2009)
Identification of the LWYIK Motif Located in the Human Immunodeficiency Virus Type 1 Transmembrane gp41 Protein as a Distinct Determinant for Viral Infection
Steve S. -L. Chen et al.
JOURNAL OF VIROLOGY (2009)
Evidence that Ecotropic Murine Leukemia Virus Contamination in TZM-bl Cells Does Not Affect the Outcome of Neutralizing Antibody Assays with Human Immunodeficiency Virus Type 1
Emily J. Platt et al.
JOURNAL OF VIROLOGY (2009)
Stable Docking of Neutralizing Human Immunodeficiency Virus Type 1 gp41 Membrane-Proximal External Region Monoclonal Antibodies 2F5 and 4E10 Is Dependent on the Membrane Immersion Depth of Their Epitope Regions
S. Moses Dennison et al.
JOURNAL OF VIROLOGY (2009)
Quantitative 3D Video Microscopy of HIV Transfer Across T Cell Virological Synapses
Wolfgang Huebner et al.
SCIENCE (2009)
Soluble CD4 and CD4-Mimetic Compounds Inhibit HIV-1 Infection by Induction of a Short-Lived Activated State
Hillel Haim et al.
PLOS PATHOGENS (2009)
The membrane proximal external region of the HIV-1 envelope glycoprotein gp41 contributes to the stabilization of the six-helix bundle formed with a matching N′ peptide
Eran Noah et al.
BIOCHEMISTRY (2008)
Hydrophobic substitutions in the first residue of the CRAC segment of the gp41 protein of HIV
Sundaram A. Vishwanathan et al.
BIOCHEMISTRY (2008)
HIV-1 broadly neutralizing antibody extracts its epitope from a kinked gp41 ectodomain region on the viral membrane
Zhen-Yu J. Sun et al.
IMMUNITY (2008)
Importance of the membrane-perturbing properties of the membrane-proximal external region of human immunodeficiency virus type 1 gp41 to viral fusion
Sundararn A. Vishwanathan et al.
JOURNAL OF VIROLOGY (2008)
Molecular architecture of native HIV-1 gp120 trimers
Jun Liu et al.
NATURE (2008)
The membrane-proximal external region of the human immunodeficiency virus type 1 envelope: Dominant site of antibody neutralization and target for vaccine design
Marinieve Montero et al.
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2008)
Analysis of the human immunodeficiency virus type 1 gp41 membrane proximal external region arrayed on hepatitis B surface antigen particles
S. Phogat et al.
VIROLOGY (2008)
Enhancing exposure of HIV-1 neutralization epitopes through mutations in gp41
Catherine A. Blish et al.
PLOS MEDICINE (2008)
Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4
Chih-chin Huang et al.
SCIENCE (2007)
Maturation-dependent human immunodeficiency virus type 1 particle fusion requires a carboxyl-terminal region of the gp41 cytoplasmic tail
Jiyang Jiang et al.
JOURNAL OF VIROLOGY (2007)
Functional links between the fusion peptide-proximal polar segment and membrane-proximal region of human immunodeficiency virus gp41 in distinct phases of membrane fusion
Anna K. Bellamy-Mclntyre et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Immunogenicity of recombinant human immunodeficiency virus type 1-like particles expressing gp41 derivatives in a pre-fusion state
Mikyung Kim et al.
VACCINE (2007)
Structural definition of a conserved neutralization epitope on HIV-1 gp120
Tongqing Zhou et al.
NATURE (2007)
Human immunodeficiency virus type 1 V1-V2 envelope loop sequences expand and add glycosylation sites over the course of infection, and these modifications affect antibody neutralization sensitivity
Manish Sagar et al.
JOURNAL OF VIROLOGY (2006)
Factors determining the breadth and potency of neutralization by V3-specific human monoclonal antibodies derived from subjects infected with clade A or clade B strains of human immunodeficiency virus type 1
C. P. Krachmarov et al.
JOURNAL OF VIROLOGY (2006)
Juxtamembrane protein segments that contribute to recruitment of cholesterol into domains
Raquel F. Epand et al.
BIOCHEMISTRY (2006)
A mutation in the human immunodeficiency virus type 1 gag protein destabilizes the interaction of the envelope protein subunits gp120 and gp41
MR Davis et al.
JOURNAL OF VIROLOGY (2006)
Human immunodeficiency virus type 1 coreceptor switching: V1/V2 gain-of-fitness mutations compensate for V3 loss-of-fitness mutations
C Pastore et al.
JOURNAL OF VIROLOGY (2006)
Maraviroc (UK-427,857), a potent, orally bioavailable, and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum anti-human immunodeficiency virus type 1 activity
P Dorr et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2005)
HIV-1 cell to cell transfer across an env-induced, actin-dependent synapse
C Jolly et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Comprehensive cross-clade neutralization analysis of a panel of anti-human immunodeficiency virus type 1 monoclonal antibodies
JA Binley et al.
JOURNAL OF VIROLOGY (2004)
Characterization of molecular features, antigen-binding, and in vitro properties of IgG and IgM variants of 4E10, an anti-HIV type 1 neutralizing monoclonal antibody
R Kunert et al.
AIDS RESEARCH AND HUMAN RETROVIRUSES (2004)
Expression and biochemical analysis of the entire HIV-2 gp41 ectodomain: determinants of stability map to N- and C-terminal sequences outside the 6-helix bundle core
CS Lay et al.
FEBS LETTERS (2004)
Regulation of human immunodeficiency virus type 1 Env-mediated membrane fusion by viral protease activity
T Murakami et al.
JOURNAL OF VIROLOGY (2004)
Intrapatient alterations in the human immunodeficiency virus type 1 gp120 V1V2 and V3 regions differentially modulate coreceptor usage, virus inhibition by CC/CXC chemokines, soluble CD4, and the b12 and 2G12 monoclonal antibodies
AA Nabatov et al.
JOURNAL OF VIROLOGY (2004)
The V1/V2 domain of gp120 is a global regulator of the sensitivity of primary human immunodeficiency virus type 1 isolates to neutralization by antibodies commonly induced upon infection
A Pinter et al.
JOURNAL OF VIROLOGY (2004)
Functional evolution of the HIV-1 envelope glycoprotein 120 association site of glycoprotein 41
P Poumbourios et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Role of the gp120 inner domain β-sandwich in the interaction between the human immunodeficiency virus envelope glycoprotein subunits
XZ Yang et al.
VIROLOGY (2003)
The dimer initiation sequence stem-loop of human immunodeficiency virus type 1 is dispensable for viral replication in peripheral blood mononuclear cells
MK Hill et al.
JOURNAL OF VIROLOGY (2003)
Redox-triggered infection by disulfide-shackled human immunodeficiency virus type 1 pseudovirions
JM Binley et al.
JOURNAL OF VIROLOGY (2003)
Human immunodeficiency virus type 1 Env with an intersubunit disulfide bond engages coreceptors but requires bond reduction after engagement to induce fusion
LG Abrahamyan et al.
JOURNAL OF VIROLOGY (2003)
Post-exposure prophylaxis with human monoclonal antibodies prevented SHIV89.6P infection or disease in neonatal macaques
F Ferrantelli et al.
AIDS (2003)
Peptides trap the human immunodeficiency virus type 1 envelope glycoprotein fusion intermediate at two sites
Y He et al.
JOURNAL OF VIROLOGY (2003)
Concordant modulation of neutralization resistance and high infectivity of the primary human immunodeficiency virus type 1 MN strain and definition of a potential gp41 binding site in gp120
M Leavitt et al.
JOURNAL OF VIROLOGY (2003)
Structural and functional roles of HIV-1 gp41 pretransmembrane sequence segmentation
A Saez-Cirion et al.
BIOPHYSICAL JOURNAL (2003)
The N-linked glycan g15 within the V3 loop of the HIV-1 external glycoprotein gp120 affects coreceptor usage, cellular tropism, and neutralization
S Polzer et al.
VIROLOGY (2002)
Antigenic properties of the human immunodeficiency virus transmembrane glycoprotein during cell-cell fusion
CM Finnegan et al.
JOURNAL OF VIROLOGY (2002)
Structural and immunological characterisation of heteroclitic peptide analogues corresponding to the 600-612 region of the HIV envelope gp41 glycoprotein
APC Du et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
Sphingomyelin and cholesterol promote HIV-1 gp41 pretransmembrane sequence surface aggregation and membrane restructuring
A Sáez-Cirión et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy
XP Wei et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2002)
Variability in the human immunodeficiency virus type 1 gp120 Env protein linked to phenotype-associated changes in the V3 loop
NG Hoffman et al.
JOURNAL OF VIROLOGY (2002)
A variable region 3 (V3) mutation determines a global neutralization phenotype and CD4-independent infectivity of a human immunodeficiency virus type 1 envelope associated with a broadly cross-reactive, primary virus-neutralizing antibody response
PF Zhang et al.
JOURNAL OF VIROLOGY (2002)
Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41
MB Zwick et al.
JOURNAL OF VIROLOGY (2001)
Functional analysis of the disulfide-bonded loop/chain reversal region of human immunodeficiency virus type 1 gp41 reveals a critical role in gp120-gp41 association
AL Maerz et al.
JOURNAL OF VIROLOGY (2001)
Sensitivity of human immunodeficiency virus type 1 to the fusion inhibitor T-20 is modulated by coreceptor specificity defined by the V3 loop of gp120
CA Derdeyn et al.
JOURNAL OF VIROLOGY (2000)
Cell fusion activity of hepatitis C virus envelope proteins
S Takikawa et al.
JOURNAL OF VIROLOGY (2000)
A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic of the trimeric virion-associated structure
JM Binley et al.
JOURNAL OF VIROLOGY (2000)
Membrane interface-interacting sequences within the ectodomain of the human immunodeficiency virus type 1 envelope glycoprotein: Putative role during viral fusion
T Suarez et al.
JOURNAL OF VIROLOGY (2000)