The Optical Coherence Tomography-Ophthalmoscope for examination of central serous chorioretinopathy with precipitates

Purpose: To report the exact location of multiple yellowish dot-like precipitates in central serous chorioretinopathy (CSC) with the Optical Coherence Tomography (OCT)-Ophthalmoscope (Nidek-OTI, Gamagori, Japan). Design: Retrospective, observational study. Methods: Twenty eyes of 18 patients (average age, 53 years) with CSC were examined by the OCT-Ophthalmoscope. Multiple yellowish dot-like precipitates were seen in all eyes by biomicroscopic examination. Results: Multiple highly reflective dots (bright dots) were seen by the OCT-Ophthalmoscope in all 20 eyes. The bright dots were observed on the posterior surface of the detached neurosensory retina by cross-sectional B-scan OCT in all eyes and in the detached neurosensory retina in 14 eyes. The bright dots were preferentially located in the outer retinal layer. Transverse C-scan OCT confirmed that the location of the bright dots coincided with that of the precipitates. Conclusions: Both cross-sectional B-scan and transverse C-scan images obtained with the OCT-Ophthalmoscope showed subretinal and intraretinal bright dots in eyes with CSC, which may indicate that the yellowish dot-like precipitates are not only on the posterior surface of the detached retina but also in the detached neurosensory retina. Intraretinal precipitates in eyes with CSC may result from the accumulation of proteins or macrophages with the phagocytized photoreceptor outer segments.