期刊
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
卷 187, 期 1, 页码 5-10出版社
ELSEVIER
DOI: 10.1016/j.resp.2013.01.013
关键词
Cigarette smoking; Inflammation; NF-kB; Oral health; COPD; IBD
资金
- Rappaport Institute
- Krol Foundation of Barnegat, NJ
- Myers-JDC-Brookdale Institute of gerontology and human development
- ESHEL - the association for planning and development of services for the aged in Israel
Despite the significant health risks resulting from tobacco use, the prevalence of smokers worldwide remains high. Cigarette smoking is one of the major sources of toxic chemical exposure to humans and is the greatest cause of preventable illnesses and premature death. The adverse consequences of smoking in various pathologies are mediated by its effects on the immune-inflammatory system. In this review, we aim to explore the effects of cigarette smoking on the inflammatory response and molecular mechanisms with emphasis on the nuclear factor kappa B (NF-kB) pathway. The effects of smoking on various inflammatory pathologies will be discussed, focusing on oral diseases, airway inflammation, chronic obstructive pulmonary disease (COPD) and inflammatory bowel diseases (IBD). (c) 2013 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据