期刊
RESPIRATION
卷 86, 期 5, 页码 384-392出版社
KARGER
DOI: 10.1159/000345859
关键词
Obstructive lung disease; Restrictive lung disease; Endurance training; 6-Minute walk distance; Maximal work rate
资金
- DGUV, German Social Accident Insurance
Background: In patients with chronic lung diseases, the work rate for endurance training is calculated by the maximal work rate (W-max). Because the assessment bears side effects, a prediction by easier accessible tests would be of practical use. Objective: We addressed the reliability of predicting W-max on the basis of the 6-min walk distance (6MWD) test and a set of further parameters in patients with different lung diseases. Methods: Baseline data of a longitudinal study including 6MWD, W max, peripheral muscle force, lung function, fat-free mass and dyspnea (Modified Medical Research Council score) of 255 men with occupational lung diseases (104 asthma, 69 asbestosis, 42 silicosis, 40 chronic obstructive pulmonary disease) were evaluated. Results: 6MWD correlated with W-max (r = 0.51, p < 0.05). The product of 6MWD and body weight, in particular fat-free mass, led to an improvement in the correlation of W-max with 6MWD. Muscle force, lung function and Modified Medical Research Council score correlated moderately but significantly with W-max (p < 0.05 each). The maximum correlation gained by including 6MWD and further parameters in the prediction equations was r = 0.76 in patients with obstructive lung function impairment and r = 0.61 in asbestosis patients. The residual standard deviations of W max predicted by the calculated equations ranged between 20 and 28 W, and the 95% prediction intervals of W-max ranged between +/- 47 and +/- 65 W. Conclusions: A reliable prediction of individual W-max by 6MWD or related measures and therefore a replacement by other tests is not possible. Nevertheless, it may be useful for the comparison of average values in epidemiological and clinical studies. Copyright (C) 2013 S. Karger AG, Basel
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据