期刊
RESEARCH ON CHEMICAL INTERMEDIATES
卷 38, 期 9, 页码 2271-2275出版社
SPRINGER
DOI: 10.1007/s11164-012-0543-8
关键词
Aldehydes; Barbituric acid; Dihydropyridine; Novel hydrogen bonding; Water chemistry
资金
- Chemistry and Chemical Research Center of Iran
- Iran National Science Foundation (INSF)
An operationally simple, atom-economical, and green procedure has been developed for the synthesis of dihydropyridine derivatives by a simple condensation of barbituric acid, aldehyde, and ammonium acetate in water under catalyst-free conditions. Excellent yields and purity were obtained with only filtration and washing with hot water and ethanol.
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