A simple phenylation of heteroaromatic compounds using diphenyliodonium triflate

In this study a novel method for direct synthesis of 2-phenyl heteroaromatic arenes was successfully developed. The title compounds were synthesized by reaction of heteroaromatic compounds with diphenylene iodonium trifluoromethanesulfonate in the presence of 5 mol% Pd(OAc)(2) under mild reaction conditions (THF, 60 A degrees C, 24 h). The proposed reaction mechanism was studied by HPLC.