期刊
RESEARCH ON CHEMICAL INTERMEDIATES
卷 37, 期 8, 页码 919-927出版社
SPRINGER
DOI: 10.1007/s11164-011-0301-3
关键词
Montmorillonite K10; Dihydroquinazolin-4(1H)-one; Antitumor studies
资金
- Department of Science & Technology Government of India [SR/FTP/CS-99/2006]
Montmorillonite K10 efficiently catalyzed a one pot-three component cyclocondensation of isatoic anhydride, NH4OAc and aromatic/heteroaromatic aldehydes under ambient conditions to produce the corresponding 2-substituted-2,3-dihydroquinazolin-4(1H)-ones in good yields. The 2-(2-chloroquinolin-3-yl)-2,3-dihydroquinazolin-4(1H)-ones 3a-d were screened for their antitumor activity against Ehrlich Ascites Carcinoma tumor cells.
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