4.6 Article

Fosfomycin susceptibility of canine methicillin-resistant Staphylococcus pseudintermedius isolates

期刊

RESEARCH IN VETERINARY SCIENCE
卷 96, 期 2, 页码 251-253

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ELSEVIER SCI LTD
DOI: 10.1016/j.rvsc.2014.02.004

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Fosfomycin; Methicillin-resistant; Staphylococcus pseudintermedius; MRSP; fosB

资金

  1. Natural Sciences and Engineering Research Council of Canada

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The effectiveness of fosfomycin was examined across 31 methicillin-resistant Staphylococcus pseudinterrnedius (MRSP) strains by agar dilution. Prevalence of the fosfomycin-resistance determinant gene, fosB, was assessed by PCR analysis. Results found that 84% of isolates were fosfomycin-susceptible. Interestingly, 87% of isolates possessed fosB, indicating no association between this putative staphylococci resistance gene and phenotypic resistance. Further evaluation of fosfomycin as a potential treatment of MRSP in dogs is warranted. (C) 2014 Elsevier Ltd. All rights reserved.

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