期刊
RESEARCH IN VETERINARY SCIENCE
卷 94, 期 3, 页码 806-808出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.rvsc.2012.11.016
关键词
Hobi-like pestivirus; Bovine viral diarrhoea virus 1; Cross-antibody response
资金
- Italian Ministry of Health
- Italian Ministry of Education, University and Research
Hobi-like pestivirus, a new tentative species within genus Pestivirus, was firstly detected in foetal bovine serum batches and later associated to respiratory distress and reproductive failures in cattle. In the present study, the cross-antibody response between bovine viral diarrhoea virus 1 (BVDV-1) and the emerging pestivirus was evaluated in the sheep model. Ten sheep were immunised against BVDV-1 or Hobi-like pestivirus using inactivated preparations and the induced antibody responses were evaluated against the homologous and heterologous viruses. The results showed that heterologous antibody titres were significantly lower than the homologous ones, thus suggesting the need to develop specific vaccines against the emerging pestiviral species. (C) 2012 Elsevier Ltd. All rights reserved.
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