期刊
RESEARCH IN MICROBIOLOGY
卷 160, 期 9, 页码 684-686出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.resmic.2009.08.015
关键词
Protein degradation; Heat shock response; Methionine biosynthesis
类别
Escherichia coli can grow at a broad temperature range, from less than 20 degrees C up to 45 degrees C. An increase in temperature results in a major physiological change, as enzymes work faster but, on the other hand, proteins tend to unfold. Therefore, a shift-up in temperature results in the induction of several regulatory response mechanisms aimed at restoring balanced growth at the new temperature. One important mechanism involves temperature-dependent proteolysis, which constitutes a fast response to temperature shift-ups. Here we discuss the effect of proteolysis on protein synthesis, and the heat shock response. (C) 2009 Elsevier Masson SAS. All rights reserved.
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