期刊
RESEARCH IN MICROBIOLOGY
卷 159, 期 5, 页码 367-373出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.resmic.2008.04.006
关键词
infant; feces; virus; phage; metagenomics; microarray; gut
类别
资金
- NSF [DBI-0308029]
Metagenomic sequencing of DNA viruses from the feces of a healthy week-old infant revealed a viral community with extremely low diversity. The identifiable sequences were dominated by phages, which likely influence the diversity and abundance of co-occurring microbes. The most abundant fecal viral sequences did not originate from breast milk or formula, suggesting a non-dietary initial source of viruses. Certain sequences were stable in the infant's gut over the first 3 months of life, but microarray experiments demonstrated that the overall viral community composition changed dramatically between I and 2 weeks of age. (C) 2008 Elsevier Masson SAS. All rights reserved.
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