Adenomyosis and 'endometrial-subendometrial myometrium unit disruption disease' are two different entities

Tile diagnosis of adenoniyosis is feasible oil pathological specimen examination, while it is 1_1111-Cliable oil clinical findings. biopsy, hysteroscopy, sonohysterography, and routine ultrasound or niagnetic resonance inia-ing. Several patterns of abnormality' described oil imaging have been linked to aderionlyosis, but the correlation is weak lind tile dia11OStiC accuracy is low outside of a research context. Nevertheless. thickening or abnorniality of tile subendometrial illyornetrillill. tile Outer part ofthe 'endoiiieti-iil-SLibt-iidoiiieti-iaI niyornetriUM unit' (thought to be important in human fertility) has been repeatedly documented oil iina,,in,,, called 'aderionlyosis' and linked to infertility. This paper discusses the Value of tile physiological endonietrial- SUbcridorrietrial niyoIlletrillul unit ill human fertility, reviews tile current criteria for its iniaging, and reports oil its relationship to fertility. It is proposed that eiidoiiieti-ial-subeiidoineti-iaI myonietrilL1111 Unit diSrUplion disease is considered -is a new entity (distinguished froin adenomyosis), the diagnosis of which is feasible and straightforward oil inia irl,, and expressed mainly by pathological thickening or abnormality of the suberidonietrial myOulCtrilull (myontetrial halo or junctional zone). The study also reports on the illflUence of abnormal thickenin', or diSl'LlfitiOll Oil human fertility and Outcome of assisted reproduction techuiqUes, and demonstrates that this riew entity is epidemiologically differciit from aderionlyosis.