期刊
REPRODUCTIVE BIOLOGY
卷 10, 期 3, 页码 249-256出版社
INST ANIMAL REPRODUCTION FOOD RESEARCH
DOI: 10.1016/S1642-431X(12)60045-X
关键词
glucocorticoids; embryo; oviduct; endometrium; trophoblast; cattle
资金
- European Union [41/2008]
- Polish Ministry of Sciences and Higher Education [308327933]
- Ministry of Agriculture, Forestry and Fisheries of Japan
We determined the transcript content of three genes involved in the metabolism of glucocorticoids (GC) in bovine in vitro fertilized embryos (2-blastomere stage until hatched blastocyst), trophoblast as well as the oviduct (Day 2-4 of the estrous cycle) and endometrium (Day 16 of the cycle and pregnancy). Since mRNA expression of the glucocorticoid receptor and two enzymes responsible for GC production (11 beta-HSD1 and 2) was demonstrated in the embryos in all pre-implantation stages as well as in the endometrium and oviduct, it is suggested that GC may serve as auto-/paracrine factors in the development of bovine pre-implantation embryos. Reproductive Biology 2010 10 3: 249-256.
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