期刊
REPRODUCTION
卷 139, 期 1, 页码 11-21出版社
BIOSCIENTIFICA LTD
DOI: 10.1530/REP-09-0083
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资金
- Royal Society
- Wellcome Trust
- BBSRC
- Biotechnology and Biological Sciences Research Council [BB/D009324/2] Funding Source: researchfish
- BBSRC [BB/D009324/2] Funding Source: UKRI
The differentiation of sperm from morphologically unremarkable cells into highly specialised free-living, motile cells requires the co-ordinated action of a very large number of gene products. The expression of these products must be regulated in a developmental context to ensure normal cellular differentiation. Many genes essential for spermatogenesis are not used elsewhere in the animal, or are expressed elsewhere, but using a different transcription regulation module. Spermatogenesis is thus a good system for elucidating the principles of tissue-specific gene expression, as well as being interesting in its own right. Here, I discuss the regulation of gene expression during spermatogenesis in Drosophila, focussing on the processes underlying the expression of testis-specific genes in the male germline. Reproduction (2010) 139 11-21
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