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Hyunjung Jade Lim et al.
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Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a mediator of multiple physiological and pathological pathways
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HB-EGF directs stromal cell polyploidy and decidualization via cyclin D-3 during implantation
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Proteolytic release of the carboxy-terminal fragment of proHB-EGF causes nuclear export of PLZF
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Mice with defects in HB-EGF ectodomain shedding show severe developmental abnormalities
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Evidence for coordinated interaction of cyclin D3 with p21 and cdk6 in directing the development of uterine stromal cell decidualization and polyploidy during implantation
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Cellular and molecular responses of the uterus to embryo implantation can be elicited by locally applied growth factors
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