期刊
REJUVENATION RESEARCH
卷 11, 期 1, 页码 177-185出版社
MARY ANN LIEBERT, INC
DOI: 10.1089/rej.2007.0614
关键词
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There is mounting evidence that as the immune system ages, a progressive deterioration in normal function occurs. Termed immunosenescence, aging impacts both the innate and adaptive immune responses. This review discusses the age-related alterations in the innate immune system, with a specific focus on macrophages. The downstream effect of altered macrophage function on aberrant angiogenesis in the pathophysiology of age-related eye disease is also discussed.
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