期刊
REGULATORY TOXICOLOGY AND PHARMACOLOGY
卷 65, 期 2, 页码 269-277出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.yrtph.2012.12.009
关键词
Mercury; Methyl mercury; Mediterranean seafood; Maximum residue limits; Tolerable intakes; Advisories
资金
- Regione Puglia, Aquafish project
- Italian Ministry of University and Research-MIUR, FISR project
- Italian Ministry of Health
Mercury (Hg) settlements in the Mediterranean Sea determine a potential toxicological relevance of seafood intakes for coastal populations. To assess this possibility, fish, molluscs, and crustaceans of commercial size of 69 different species were sampled and analyzed for total mercury (Hg-TOT) from georeferenced areas and evaluated for their compliance with the European Union Maximum Residue Limits of 0.5 and 1.0 mg/kg wet weight (ww). Accounting for the weekly estimated seafood intake in the Italian coastal population (mean 469-626 g/person/week) it was then possible to recover threshold contamination values in seafood. Under a Tolerable Weekly Intake of 1.3 mu g/kg/bw/week, a threshold seafood contamination <0.10 mg/kg ww has been derived for sensitive groups. A suitable algorithm based on the parallel MeHg and Hg-TOT analysis on the most consumed species, helped to refine the uncertainties related to the conservative assumption in seafood all the Hg-TOT present is in form of MeHg. This work aims to improve the link between the risk management and risk assessment strategies, with the identification of those fish and seafood species, that, when regularly consumed, could determine or prevent potential Hg-TOT/MeHg overintakes in sensitive groups. (C) 2013 Elsevier Inc. All rights reserved.
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