期刊
REGENERATIVE MEDICINE
卷 6, 期 4, 页码 469-479出版社
FUTURE MEDICINE LTD
DOI: 10.2217/RME.11.37
关键词
embryonic stem cell; eye; induced pluripotent stem cell; nuclear reprogramming; photoreceptor; regeneration; retina; retinal degeneration; retinitis pigmentosa
资金
- Medical Research Council [G0700438, G0901550] Funding Source: Medline
- MRC [G0901550, G0700438] Funding Source: UKRI
- Medical Research Council [G0901550, G0700438] Funding Source: researchfish
- National Institute for Health Research [NF-SI-0508-10130] Funding Source: researchfish
The discovery of methods to produce pluripotent stem cells from human skin cells and other adult tissues has created a new era in stem cell research. In this article, we discuss the generation and use of pluripotent stem cells for the study of retinal disorders and the development of cell-based therapies. We describe advances in protocols for differentiating pluripotent cells into photoreceptor precursors that might be suitable for transplantation and discuss the use of human induced pluripotent stem cell-derived photoreceptors for disease modeling and drug screening.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据