期刊
RADIOTHERAPY AND ONCOLOGY
卷 95, 期 3, 页码 277-282出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.radonc.2010.04.016
关键词
Endorectal balloon; Prostate cancer; Radiotherapy; Rectal wall sparing; Anorectal toxicity
资金
- Dutch Cancer Society [KUN 2008-4239]
Background and purpose: Endorectal balloons (ERBs) are being used in prostate radiotherapy for prostate immobilization and rectal wall (Rwall) sparing. Some of their aspects, however, have been questioned, like patient's tolerance and their value in modern high-precision radiotherapy. This paper gives an overview of published data concerning ERB application in prostate radiotherapy. Materials and methods: Systematic literature review based on PubMed/MEDLINE database searches. Results: Overall, ERBs are tolerated well, although patients with pre-existing anorectal disease have an increased risk of developing ERB-related toxicity. Planning studies show reduced Rwall and anal wall (Awall) doses with ERB application. Clinical data, however, are scarce, as only one study shows reduced late rectal damage. There is no consensus about the immobilizing properties of ERBs and it is recommended to use additional set-up and correction protocols, especially because there are potential pitfalls. Conclusion: ERBs seem well-tolerated and in planning studies reduce anorectal wall doses. This may lead to reduced anorectal toxicity, although clinical studies are warranted to confirm this hypothesis and to further investigate the immobilizing properties of ERBs, preferably in combination with advanced techniques for position verification. (C) 2010 Elsevier Ireland Ltd. All rights reserved. Radiotherapy and Oncology 95 (2010) 277-282
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据