期刊
RADIATION ONCOLOGY
卷 7, 期 -, 页码 -出版社
BMC
DOI: 10.1186/1748-717X-7-162
关键词
Wound healing; Radiation therapy
Radiation therapy is an established modality in the treatment of head and neck cancer patients. Compromised wound healing in irradiated tissues is a common and challenging clinical problem. The pathophysiology and underlying cellular mechanisms including the complex interaction of cytokines and growth factors are still not understood completely. In this review, the current state of research regarding the pathomechanisms of compromised wound healing in irradiated tissues is presented. Current and possible future treatment strategies are critically reviewed.
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