MODERN TECHNIQUES OF SAMPLE PREPARATION FOR PESTICIDE RESIDUES DETERMINATION IN WATER BY LIQUID CHROMATOGRAPHY WITH DETECTION BY DIODE ARRAY AND MASS SPECTROMETRY

MODERN TECHNIQUES OF SAMPLE PREPARATION FOR PESTICIDE RESIDUES DETERMINATION IN WATER BY LIQUID CHROMATOGRAPHY WITH DETECTION BY DIODE ARRAY AND MASS SPECTROMETRY. The determination of pesticide residues in water samples by Liquid Chromatography require sample preparation for extraction and enrichment of the analytes with the minimization of interferences to achieve adequate detection limits. The Solid Phase Extraction (SPE), Solid Phase Microextraction (SPME), Stir Bar Sorptive Extraction (SBSE) and Dispersive Liquid-Liquid Microextraction (DLLME) techniques have been widely used for extraction of pesticides in water. In this review, the principles of these sample preparation techniques associated with the analysis by Liquid Chromatography with Diode Array Detection (LC-DAD) or Mass Spectrometry (LC-MS) are described and an overview of several applications were presented and discussed.