期刊
QUIMICA NOVA
卷 32, 期 1, 页码 78-81出版社
SOC BRASILEIRA QUIMICA
DOI: 10.1590/S0100-40422009000100015
关键词
Annona foetida; antimicrobial and antileishmanial activities; essential oil composition
资金
- CAPES/RENOR
- CNPq/PADCT
The essential oil from leaves of Annona foetida obtained by hydrodistillation was analyzed by GC/FID and GC/MS. The results showed that the major constituents were bicyclogermacrene (35.12%), (E)-caryophyllene (14.19%) and alpha-copaene (8.19%). The antimicrobial and antileishmanial activities were investigated. The oil showed potent antimicrobial activity against Candida albicans and Rhodococcus equi. The oil also showed significant antileishmanial activity, giving the best results against Leishmania guyanensis. A preliminary cytotoxicity assay for this oil was carried out on hamster and mice (Balb/c) peritoneal macrophages. The results obtained were similar to pentamidine and considered not to be cytotoxic to macrophages.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据