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PURINERGIC SIGNALLING (2007)
Bilayer mechanical properties regulate the transmembrane helix mobility and enzymatic state of CD39
Alison Grinthal et al.
BIOCHEMISTRY (2007)
Characterization of an alternative splice variant of human nucleoside triphosphate diphosphohydrolase 3 (NTPDase3): A possible modulator of nucleotidase activity and purinergic signaling
Patrick A. Crawford et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2007)
Nucleotide pyrophosphatase/phosphodiesterase 1 is responsible for degradation of antisense phosphorothioate oligonucleotides
Marzena Wojcik et al.
OLIGONUCLEOTIDES (2007)
Physiology and pathophysiology of purinergic neurotransmission
Geoffrey Burnstock
PHYSIOLOGICAL REVIEWS (2007)
NTPDase and 5 '-nucleotidase activities in physiological and disease conditions: New perspectives for human health
Maria Rosa C. Schetinger et al.
BIOFACTORS (2007)
Interleukin-3 promotes the expression of E-NPP3/CD203C on human blood basophils in healthy subjects and in patients with birch pollen allergy
A. W. Hauswirth et al.
INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY (2007)
Secretion and lysophospholipase D activity of autotaxin by adipocytes are controlled by N-glycosylation and signal peptidase
Jean Philippe Pradere et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2007)
Activation-dependent trafficking of NTPDase2 in Chinese hamster ovary cells
Srdjan M. Vlajkovic et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2007)
Mechanisms of disease: ectonucleotide pyrophosphatase phosphodiesterase 1 as a 'gatekeeper' of insulin receptors
Nicola Abate et al.
NATURE CLINICAL PRACTICE ENDOCRINOLOGY & METABOLISM (2006)
Adenosine 5′-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation
M. J. L. Bours et al.
PHARMACOLOGY & THERAPEUTICS (2006)
ATP-consuming and ATP-generating enzymes secreted by pancreas
Gennady G. Yegutkin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor
Paolo Ciana et al.
EMBO JOURNAL (2006)
Trapping the tetrahedral intermediate in the alkaline phosphatase reaction by substitution of the active site serine with threonine
Jie Wang et al.
PROTEIN SCIENCE (2006)
Cyclic phosphatidic acid is produced by autotaxin in blood
Satomi Tsuda et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid
Masayuki Tanaka et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Post- and prejunctional consequences of ecto-ATPase inhibition: electrical and contractile studies in guinea-pig vas deferens
P. Ghildyal et al.
JOURNAL OF PHYSIOLOGY-LONDON (2006)
Structural and functional comparisons of nucleotide pyrophosphatase/phosphodiesterase and alkaline phosphatase: Implications for mechanism and evolution
Jesse G. Zalatan et al.
BIOCHEMISTRY (2006)
Mammalian alkaline phosphatase catalysis requires active site structure stabilization via the N-terminal amino acid microenvironment
Marc F. Hoylaerts et al.
BIOCHEMISTRY (2006)
The detection of micromolar pericellular ATP pool on lymphocyte surface by using lymphoid ecto-adenylate kinase as intrinsic ATP sensor
Gennady G. Yegutkin et al.
MOLECULAR BIOLOGY OF THE CELL (2006)
Nucleoside transporters: from scavengers to novel therapeutic targets
Anne E. King et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2006)
Dinucleoside polyphosphates and their interaction with other nucleotide signaling pathways
Esmerilda G. Delicado et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2006)
Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development
Laurens A. van Meeteren et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Nucleoside triphosphate diphosphohydrolase-2 is the ecto-ATPase of type I cells in taste buds
Dianna L. Bartel et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2006)
Zinc transport complexes contribute to the homeostatic maintenance of secretory pathway function in vertebrate cells
Kaori Ishihara et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Autotaxin is overexpressed in glioblastoma multiforme and contributes to cell motility of glioblastoma by converting lysophosphatidylcholine TO lysophosphatidic acid
Yasuhiro Kishi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Molecular cloning and characterization of expressed human ecto-nucleoside triphosphate diphosphohydrolase 8 (E-NTPDase 8) and its soluble extracellular domain
Aileen F. Knowles et al.
BIOCHEMISTRY (2006)
RanBPM associates with CD39 and modulates ecto-nucleotidase activity
Yan Wu et al.
BIOCHEMICAL JOURNAL (2006)
Comparative genomic and expression analysis of the conserved NTPDase gene family in Xenopus
K Massé et al.
GENOMICS (2006)
Pathophysiology and therapeutic potential of purinergic signaling
G Burnstock
PHARMACOLOGICAL REVIEWS (2006)
Intestinal alkaline sphingomyelinase hydrolyses and inactivates platelet-activating factor by a phospholipase C activity
J Wu et al.
BIOCHEMICAL JOURNAL (2006)
Immunolocalization of ectonucleotidases along the rat nephron
RM Vekaria et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2006)
On the role and fate of LPS-dephosphorylating activity in the rat liver
A Tuin et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2006)
Extracellular nucleotide signaling in adult neural stem cells:: synergism with growth factor-mediated cellular proliferation
SK Mishra et al.
DEVELOPMENT (2006)
The N-terminal hydrophobic sequence of autotaxin (ENPP2) functions as a signal peptide
S Koike et al.
GENES TO CELLS (2006)
Immunolocalization of ecto-nucleoside triphosphate diphosphohydrolase 3 in rat brain: Implications for modulation of multiple homeostatic systems including feeding and sleep-wake behaviors
SM Belcher et al.
NEUROSCIENCE (2006)
International union of pharmacology LVIII: Update on the P2Y G protein-coupled nucleotide receptors: From molecular mechanisms and pathophysiology to therapy
Maria P. Abbracchio et al.
PHARMACOLOGICAL REVIEWS (2006)
Ecto-F1F0 ATP synthase/F-1 ATPase: metabolic and immunological functions
Eric Champagne et al.
CURRENT OPINION IN LIPIDOLOGY (2006)
The increased ecto-5 '-nucleotidase activity in muscle, heart and liver of laminin alpha 2-deficient mice is not caused by an elevation in the mRNA content
Julio C. Morote-Garcia et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2006)
Phosphodiesterase-Iα-/autotaxin (PD-Iα/ATX):: A multifunctional protein involved in central nervous system development and disease
J Dennis et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2005)
NPP-type ectophosphodiesterases: unity in diversity
C Stefan et al.
TRENDS IN BIOCHEMICAL SCIENCES (2005)
Cell-surface enzymes in control of leukocyte trafficking
M Salmi et al.
NATURE REVIEWS IMMUNOLOGY (2005)
Two different zinc transport complexes of cation diffusion facilitator proteins localized in the secretory pathway operate to activate alkaline phosphatases in vertebrate cells
T Suzuki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Either the carboxyl- or the amino-terminal region of the human ecto-ATPase (E-NTPDase 2) confers detergent and temperature sensitivity to the chicken ecto-ATP-diphosphohydrolase (E-NTPDase 8)
T Mukasa et al.
BIOCHEMISTRY (2005)
Structural studies of human placental alkaline phosphatase in complex with functional ligands
P Llinas et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
Human tartrate-resistant acid phosphatase becomes an effective ATPase upon proteolytic activation
N Mitic et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2005)
Cholesterol-dependent lipid assemblies regulate the activity of the ecto-nucleotidase CD39
A Papanikolaou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Proteolytic maturation and activation of autotaxin (NPP2), a secreted metastasis-enhancing lysophospholipase D
S Jansen et al.
JOURNAL OF CELL SCIENCE (2005)
The 5′-nucleotidases as regulators of nucleotide and drug metabolism
SA Hunsucker et al.
PHARMACOLOGY & THERAPEUTICS (2005)
Characterization of disulfide bonds in human nucleoside triphosphate diphosphohydrolase 3 (NTPDase3): Implications for NTPDase structural modeling
VV Ivanenkov et al.
BIOCHEMISTRY (2005)
Portal fibroblasts regulate the proliferation of bile duct epithelia via expression of NTPDase2
MN Jhandier et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Biochemical and molecular characterization of a novel choline-specific glycerophosphodiester phosphodiesterase belonging to the nucleotide pyrophosphatase/phosphodiesterase family
H Sakagami et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate
LA van Meeteren et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Functional expression of the ecto-ATPase NTPDase2 and of nucleotide receptors by neuronal progenitor cells in the adult murine hippocampus
V Shukla et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2005)
Sustained osteomalacia of long bones despite major improvement in other hypophosphatasia-related mineral deficits in tissue nonspecific alkaline phosphatase/nucleoticle pyrophosphatase phosphodiesterase 1 double-deficient mice
HC Anderson et al.
AMERICAN JOURNAL OF PATHOLOGY (2005)
Postnatal development of alkaline phosphatase activity correlates with the maturation of neurotransmission in the cerebral cortex
C Fonta et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2005)
Distinctive roles of endoplasmic reticulum and golgi glycosylation in functional surface expression of mammalian E-NTPDasel, CD39
XT Zhong et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2005)
Raft partitioning and dynamic behavior of human placental alkaline phosphatase in giant unilamellar vesicles
N Kahya et al.
BIOCHEMISTRY (2005)
Ectonucleoside triphosphate diphosphohydrolase1/CD39, localized in neurons of human and porcine heart, modulates ATP-induced norepinephrine exocytosis
T Machida et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
N-linked oligosaccharides affect the enzymatic activity of CD39:: Diverse interactions between seven N-linked glycosylation sites
JJ Wu et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Ectonucleotidases of CD39 family modulate vascular inflammation and thrombosis in transplantation
SC Robson et al.
SEMINARS IN THROMBOSIS AND HEMOSTASIS (2005)
Role of CD39 (NTPDase-1) in thromboregulation, cerebroprotection, and cardioprotection
AJ Marcus et al.
SEMINARS IN THROMBOSIS AND HEMOSTASIS (2005)
Chondrogenesis mediated by PPi depletion promotes spontaneous aortic calcification in NPP1-/- mice
K Johnson et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2005)
Bacterial expression, folding, purification and characterization of soluble NTPDase5 (CD39L4) ecto-nucleotidase
DM Murphy-Piedmonte et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2005)
A large hinge bending domain rotation is necessary for the catalytic function of Escherichia coli 5′-nucleotidase
R Schultz-Heienbrok et al.
BIOCHEMISTRY (2005)
Functional studies of human intestinal alkaline sphingomyelinase by deglycosylation and mutagenesis
J Wu et al.
BIOCHEMICAL JOURNAL (2005)
Adenovirus-mediated transfer of human placental ectonucleoside triphosphate diphosphohydrolase to vascular smooth muscle cells suppresses platelet aggregation in vitro and arterial thrombus formation in vivo
E Furukoji et al.
CIRCULATION (2005)
C-terininal splicing of NTPDase2 provides distinctive catalytic properties, cellular distribution and enzyme regulation
CJF Wang et al.
BIOCHEMICAL JOURNAL (2005)
Identification of autotaxin as a neurite retraction-inducing factor of PC12 cells in cerebrospinal fluid and its possible sources
K Sato et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Zinc transporters, ZnT5 and ZnT7, are required for the activation of alkaline phosphatases, zinc-requiring enzymes that are glycosylphosphatidylinositol-anchored to the cytoplasmic membrane
T Suzuki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Effects of tunicamycin, mannosamine, and other inhibitors of glycoprotein processing on skeletal alkaline phosphatase in human osteoblast-like cells
JR Farley et al.
CALCIFIED TISSUE INTERNATIONAL (2005)
Inorganic pyrophosphate (PPI) in pathologic calcification of articular cartilage
K Johnson et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2005)
Regulation of P2Y(1) receptor-mediated signaling by the ectonucleoside triphosphate diphosphohydrolase isozymes NTPDase1 and NTPDase2
C Alvarado-Castillo et al.
MOLECULAR PHARMACOLOGY (2005)
Thromboregulatory manifestations in human CD39 transgenic mice and the implications for thrombotic disease and transplantation
KM Dwyer et al.
JOURNAL OF CLINICAL INVESTIGATION (2004)
Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1
K Hama et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Cystic fibrosis transmembrane conductance regulator in human and mouse red blood cell membranes and its interaction with ecto-apyrase
KM Sterling et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2004)
Active and inactive ecto-5′-nucleotidase variants in liver of control and dystrophic Lama2dy mice
JC Morote-García et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)
Impaired calcification around matrix vesicles of growth plate and bone in alkaline phosphatase-deficient mice
HC Anderson et al.
AMERICAN JOURNAL OF PATHOLOGY (2004)
HMM Logos for visualization of protein families -: art. no. 7
B Schuster-Böckler et al.
BMC BIOINFORMATICS (2004)
Association of the Ecto-ATPase NTPDase2 with glial cells of the peripheral nervous system
N Braun et al.
GLIA (2004)
Mechanisms of lysophosphatidic acid production
J Aoki
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2004)
Phosphodieterase-Iα/autotaxin and IFAK phosphorylation during controls cytoskeletal organization myelination
MA Fox et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2004)
Ligand-binding and metal-exchange crystallographic studies on shrimp alkaline phosphatase
MME de Backer et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)
A nucleotidase with unique catalytic properties is secreted by Trichinella spiralis
K Gounaris et al.
MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2004)
Crucial role for ecto-5-′nucleotidase (CD73) in vascular leakage during hypoxia
LF Thompson et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Trapping a 96° domain rotation in two distinct conformations by engineered disulfide bridges
R Schultz-Heienbrok et al.
PROTEIN SCIENCE (2004)
Characterization of the ATP-hydrolysing activity of α-sarcoglycan
D Sandonà et al.
BIOCHEMICAL JOURNAL (2004)
ATP and ATPase secretion by exocrine pancreas in rat, guinea pig, and human
KS Kordás et al.
PANCREAS (2004)
Localization of nucleoside triphosphate diphosphohydrolase-1 (NTPDase1) and NTPDase2 in pancreas and salivary gland
A Kittel et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2004)
Substrate-specifying determinants of the nucleotide pyrophosphatases/phosphodiesterases NPP1 and NPP2
A Cimpean et al.
BIOCHEMICAL JOURNAL (2004)
Dynamic motions of CD39 transmembrane domains regulate and are regulated by the enzymatic active site
A Grinthal et al.
BIOCHEMISTRY (2004)
Pancreatic trypsin cleaves intestinal alkaline sphingomyelinase from mucosa and enhances the sphingomyelinase activity
J Wu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2004)
Mapping quantitative trait loci that influence blood levels of alkaline phosphatase in MRL/MpJ and SJL/J mice
AK Srivastava et al.
BONE (2004)
Residues determining the binding specificity of uncompetitive inhibitors to tissue-nonspecific alkaline phosphatase
A Kozlenkov et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2004)
Disulfide bonding arrangements in active forms of the somatomedin B domain of human vitronectin
Y Kamikubo et al.
BIOCHEMISTRY (2004)
Targeted disruption of cd73/ecto-5′-nucleotidase alters thromboregulation and augments vascular inflammatory response
P Koszalka et al.
CIRCULATION RESEARCH (2004)
Triatoma infestans apyrases belong to the 5′-Nucleotidase family
E Faudry et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Metabolism of P2 receptor agonists in human airways - Implications for mucociliary clearance and cystic fibrosis
M Picher et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Subcellular targeting and function of osteoblast nucleotide pyrophosphatase phosphodiesterase 1
SM Vaingankar et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2004)
The basophil-specific ectoenzyme E-NPP3 (CD203c) as a marker for cell activation and allergy diagnosis
HJ Buhring et al.
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY (2004)
Mammalian 5′-nucleotidases
V Bianchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Asparagine 81, an invariant glycosylation site near apyrase conserved region 1, is essential for full enzymatic activity of ecto-nucleoside triphosphate diphosphohydrolase (vol 413, pg 107, 2003)
DM Murphy et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2003)
Enzymatic and transcriptional regulation of human ecto-ATPase/E-NTPDase 2
AF Knowles et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2003)
Bacterial expression, characterization, and disulfide bond determination of soluble human NTPDase6 (CD39L2) nucleotidase: Implications for structure and function
VV Ivanenkov et al.
BIOCHEMISTRY (2003)
Requirement of Cys399 for processing of the human ecto-ATPase (NTPDase2) and its implications for determination of the activities of splice variants of the enzyme
J Mateo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Identification of human intestinal alkaline sphingomyelinase as a novel ecto-enzyme related to the nucleotide phosphodiesterase family
RD Duan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
NAD-induced T cell death: ADP-ribosylation of cell surface proteins by ART2 activates the cytolytic P2X7 purinoceptor
M Seman et al.
IMMUNITY (2003)
A β-N-acetylglucosaminyl phosphate diester residue is attached to the glycosylphosphatidylinositol anchor of human placental alkaline phosphatase -: A target of the channel-forming toxin aerolysin
K Fukushima et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Rat pancreas secretes particulate ecto-nucleotidase CD39
CE Sorensen et al.
JOURNAL OF PHYSIOLOGY-LONDON (2003)
Characterization of nucleotide pyrophosphatase-5 as an oligomannosidic glycoprotein in rat brain
Y Ohe et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Hydrolysis of diadenosine polyphosphates by nucleotide pyrophosphatases/phosphodiesterases
P Vollmayer et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2003)
Lysophosphatidic acid signaling: how a small lipid does big things
C Luquain et al.
TRENDS IN BIOCHEMICAL SCIENCES (2003)
Phosphodiesterase-Iα/autotaxin:: a counteradhesive protein expressed by oligodendrocytes during onset of myelination
MA Fox et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2003)
Cobalt activation of Escherichia coli 5′-nucleotidase is due to zinc ion displacement at only one of two metal-ion-binding sites
L McMillen et al.
BIOCHEMICAL JOURNAL (2003)
Biochemical and mass spectrometric characterization of soluble ecto-5′-nucleotidase from bull seminal plasma
C Fini et al.
BIOCHEMICAL JOURNAL (2003)
Physiological and pathophysiological functions of the ecto-nucleotide pyrophosphatase/phosphodiesterase family
JW Goding et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2003)
Functional characterization of the non-catalytic ectodomains of the nucleotide pyrophosphatase/phosphodiesterase NPP1
R Gijsbers et al.
BIOCHEMICAL JOURNAL (2003)
Ecto 5′-nucleotidase and nonspecific alkaline phosphatase -: Two amp-hydrolyzing ectoenzymes with distinct roles in human airways
M Picher et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Expression of the ecto-ATPase NTPDase2 in the germinal zones of the developing and adult rat brain
N Braun et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2003)
Determination of native oligomeric state and substrate specificity of rat NTPDase1 and NTPDase2 after heterologous expression in Xenopus oocytes
BU Failer et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2003)
The hydrolysis of lysophospholipids and nucleotides by autotaxin (NPP2) involves a single catalytic site
R Gijsbers et al.
FEBS LETTERS (2003)
Structural evidence of functional divergence in human alkaline phosphatases
MH Le Du et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Serum lysophosphatidic acid is produced through diverse phospholipase pathways
J Aoki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Differences in sialic acid residues among bone alkaline phosphatase isoforms: A physical, biochemical, and immunological characterization
P Magnusson et al.
CALCIFIED TISSUE INTERNATIONAL (2002)
ATP as a cotransmitter in sympathetic nerves and its inactivation by releasable enzymes
DP Westfall et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2002)
Different distributions of human bone alkaline phosphatase isoforms in serum and bone tissue extracts
P Magnusson et al.
CLINICA CHIMICA ACTA (2002)
Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase
A Tokumura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Roles of Asp54 and Asp213 in Ca2+ utilization by soluble human CD39/ecto-nucleotidase
JHF Drosopoulos
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2002)
A fusion protein of the human P2Y1 receptor and NTPDase1 exhibits functional activities of the native receptor and ectoenzyme and reduced signaling
C Alvarado-Castillo et al.
MOLECULAR PHARMACOLOGY (2002)
Placental alkaline phosphatase is efficiently targeted to rafts in supported lipid bilayers
DE Saslowsky et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production
M Umezu-Goto et al.
JOURNAL OF CELL BIOLOGY (2002)
Function assignment to conserved residues in mammalian alkaline phosphatases
A Kozlenkov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The 1.9 Å crystal structure of heat-labile shrimp alkaline phosphatase
M de Backer et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
Differential catalytic properties and vascular topography of murine nucleoside triphosphate diphosphohydrolase 1 (NTPDase1) and NTPDase2 have implications for thromboregulation
J Sévigny et al.
BLOOD (2002)
CD39 is the dominant Langerhans cell associated ecto-NTPDase:: Modulatory roles in inflammation and immune responsiveness
N Mizumoto et al.
NATURE MEDICINE (2002)
Identification of cysteine residues responsible for oxidative crosslinking and chemical inhibition of human nucleoside-triphosphate diphosphohydrolase 3
DM Murphy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Transmembrane domains confer different substrate specificities and adenosine diphosphate hydrolysis mechanisms on CD39, CD39L1, and chimeras
A Grinthal et al.
BIOCHEMISTRY (2002)
Artificial evolution of an enzyme active site: Structural studies of three highly active mutants of Escherichia coli alkaline phosphatase
MH Le Du et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
Disordered cellular migration and angiogenesis in cd39-null mice
C Goepfert et al.
CIRCULATION (2001)
Conserved core structure and active site residues in alkaline phosphatase superfamily enzymes
MY Galperin et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2001)
The GPI-anchor and protein sorting
S Chatterjee et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2001)
Identification of inactive ecto-5′-nucleotidase in normal mouse muscle and its increased activity in dystrophic Lama2dy mice
MS García-Ayllón et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2001)
Mammalian plasma membrane ecto-nucleoside triphosphate diphosphohydrolase 1, CD39, is not active intracellularly -: The N-glycosylation state of CD39 correlates with surface activity and localization
XT Zhong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Site-directed mutagenesis of human nucleoside triphosphate diphosphohydrolase 3: The importance of conserved glycine residues and the identification of additional conserved protein motifs in eNTPDases
TL Kirley et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2001)
Characterization of a di-leucine-based signal in the cytoplasmic tail of the nucleotide-pyrophosphatase NPP1 that mediates basolateral targeting but not endocytosis
V Bello et al.
MOLECULAR BIOLOGY OF THE CELL (2001)
Quantitation of soluble and skeletal alkaline phosphatase, and insoluble alkaline phosphatase anchor-hydrolase activities in human serum
DJ Anh et al.
CLINICA CHIMICA ACTA (2001)
Structural evidence for a functional role of human tissue nonspecific alkaline phosphatase in bone mineralization
E Mornet et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Enzymatic activation of autotaxin by divalent cations without EF-hand loop region involvement
J Lee et al.
BIOCHEMICAL PHARMACOLOGY (2001)
Mechanism of hydrolysis of phosphate esters by the dimetal center of 5′-nucleotidase based on crystal structures
T Knöfel et al.
JOURNAL OF MOLECULAR BIOLOGY (2001)
E-coli 5′-nucleotidase undergoes a hinge-bending domain rotation resembling a ball-and-socket motion
T Knöfel et al.
JOURNAL OF MOLECULAR BIOLOGY (2001)
Molecular cloning and characterization of a novel mammalian endo-apyrase (LALP1)
JD Shi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Functional interrelationships in the alkaline phosphatase superfamily:: phosphodiesterase activity of Escherichia coli alkaline phosphatase
PJ O'Brien et al.
BIOCHEMISTRY (2001)
The basophil activation marker defined by antibody 97A6 is identical to the ectonucleotide pyrophosphatase/phosphodiesterase 3
HJ Bühring et al.
BLOOD (2001)
The importance of histidine residues in human ecto-nucleoside triphosphate diphosphohydrolase-3 as determined by site-directed mutagenesis
CA Hicks-Berger et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY (2001)
Site-directed mutagenesis of human nucleoside triphosphate diphosphohydrolase 3: The importance of residues in the apyrase conserved regions
F Yang et al.
BIOCHEMISTRY (2001)
Soluble apyrases release ADP during ATP hydrolysis
W Chen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Crystal structure of alkaline phosphatase from human placenta at 1.8 A resolution -: Implication for a substrate specificity
MH Le Du et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Structural and catalytic similarities between nucleotide pyrophosphatases/phosphodiesterases and alkaline phosphatases
R Gijsbers et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Ectonucleotidases: Some recent developments and a note on nomenclature
H Zimmermann
DRUG DEVELOPMENT RESEARCH (2001)
Diadenosine polyphosphates as extracellular signal molecules
CHV Hoyle et al.
DRUG DEVELOPMENT RESEARCH (2001)
Erythrocyte membrane ATP binding cassette (ABC) proteins: MRP1 and CFTR as well as CD39 (ecto-apyrase) involved in RBC ATP transport and elevated blood plasma ATP of cystic fibrosis
EH Abraham et al.
BLOOD CELLS MOLECULES AND DISEASES (2001)
Urkinase: Structure of acetate kinase, a member of the ASKHA superfamily of phosphotransferases
KA Buss et al.
JOURNAL OF BACTERIOLOGY (2001)
Extracellular ATP formation on vascular endothelial cells is mediated by ecto-nucleotide kinase activities via phosphotransfer reactions
GG Yegutkin et al.
FASEB JOURNAL (2001)
The role and regulation of adenosine in the central nervous system
TV Dunwiddie et al.
ANNUAL REVIEW OF NEUROSCIENCE (2001)
Ecto-alkaline phosphatase in NG108-15 cells: a key enzyme mediating P1 antagonist-sensitive ATP response
S Ohkubo et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)
CD73 engagement promotes lymphocyte binding to endothelial cells via a lymphocyte function-associated antigen-1-dependent mechanism
L Airas et al.
JOURNAL OF IMMUNOLOGY (2000)
Expression and characterization of soluble and membrane-bound human nucleoside triphosphate diphosphohydrolase 6 (CH39L2)
CA Hicks-Berger et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Sequencing, functional expression and characterization of rat NTPDase6, a nucleoside diphosphatase and novel member of the ecto-nucleoside triphosphate diphosphohydrolase family
N Braun et al.
BIOCHEMICAL JOURNAL (2000)
Structure, function, and regulation of tartrate-resistant acid phosphatase
GW Oddie et al.
BONE (2000)
Biochemical characterization of CD39L4
JJ Mulero et al.
BIOCHEMISTRY (2000)
CD39L2, a gene encoding a human nucleoside diphosphatase, predominantly expressed in the heart
G Yeung et al.
BIOCHEMISTRY (2000)
Placental alkaline phosphatase, insulin, and adenine nucleotides or adenosine synergistically promote long-term survival of serum-starved mouse embryo and human fetus fibroblasts
QB She et al.
CELLULAR SIGNALLING (2000)
T-Coffee: A novel method for fast and accurate multiple sequence alignment
C Notredame et al.
JOURNAL OF MOLECULAR BIOLOGY (2000)
Promoter sequences of the putative Anopheles gambiae apyrase confer salivary gland expression in Drosophila melanogaster
F Lombardo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Tumor-promoting functions of adenosine
J Spychala
PHARMACOLOGY & THERAPEUTICS (2000)
Biochemical evidence for an ecto alkaline phosphodiesterase I in human airways
M Picher et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2000)
Mass spectrometry study of ecto-5′-nucleotidase from bull seminal plasma
C Fini et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2000)
ATP crossing the cell plasma membrane generates an ionic current in Xenopus oocytes
E Bodas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
First apyrase splice variants have different enzymatic properties
A Biederbick et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
A revised mechanism for the alkaline phosphatase reaction involving three metal ions
B Stec et al.
JOURNAL OF MOLECULAR BIOLOGY (2000)
Site-directed mutagenesis of human endothelial cell ecto-ADPase/soluble CD39: Requirement of glutamate 174 and serine 218 for enzyme activity and inhibition of platelet recruitment
JHF Drosopoulos et al.
BIOCHEMISTRY (2000)
The ecto-5′-nucleotidase subunits in dimers are not linked by disulfide bridges but by non-covalent bonds
A Martínez-Martínez et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY (2000)
Ecto-nucleotide pyrophosphatase modulates the purinoceptor-mediated signal transduction and is inhibited by purinoceptor antagonists
B Grobben et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)
Palmitoylation targets CD39/endothelial ATP diphosphohydrolase to caveolae
K Koziak et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Substitution of His59 converts CD39 apyrase into an ADPase in a quaternary structure dependent manner
A Grinthal et al.
BIOCHEMISTRY (2000)
Effect of shear stress on the release of soluble ecto-enzymes ATPase and 5 '-nucleotidase along with endogenous ATP from vascular endothelial cells
G Yegutkin et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)
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