期刊
PURE AND APPLIED CHEMISTRY
卷 80, 期 8, 页码 1703-1718出版社
INT UNION PURE APPLIED CHEMISTRY
DOI: 10.1351/pac200880081703
关键词
nanoparticles; responsiveness; polysulfides; inflammation; oxidation
资金
- Biotechnology and Biological Sciences Research Council [BBS/B/01537] Funding Source: researchfish
Oxidation is an almost ubiquitous feature of inflammatory reactions. We discuss the development of nanocarriers that respond to the presence of oxidants with profound physical reorganization, which could in perspective allow their use for delivering anti-inflammatory principles in an inflammation-responsive fashion. We also present a study demonstrating that the response of polysulfide nanoparticles has a bulk character, i.e., the odixation reactions happen homogeneously throughout the nanoparticles, and not interfacially.
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