期刊
PSYCHOTHERAPY AND PSYCHOSOMATICS
卷 80, 期 5, 页码 287-297出版社
KARGER
DOI: 10.1159/000323466
关键词
Cannabis; Psychological intervention; Psychosis; Schizophrenia; Substance use disorders; Randomized controlled trial
资金
- Swiss Research National Fund (FNS) [3200BO-108454]
- Leenaards Foundation in Lausanne, Switzerland
Background: Cannabis use has a negative impact on psychosis. Studies are needed to explore the efficacy of psychological interventions to reduce cannabis use in psychosis. Our aim is to study the efficacy of a specific motivational intervention on young cannabis users suffering from psychosis. Methods: Participants (aged less than 35 years) were randomly assigned to treatment as usual (TAU) alone, or treatment as usual plus motivational intervention (MI + TAU). TAU was comprehensive and included case management, early intervention and mobile team when needed. Assessments were completed at baseline and at 3, 6 and 12 months follow-up. Results: Sixty-two participants (32 TAU and 30 MI + TAU) were included in the study. Cannabis use decreased in both groups at follow-up. Participants who received MI in addition to TAU displayed both a greater reduction in number of joints smoked per week and greater confidence to change cannabis use at 3 and 6 months follow-up, but differences between groups were nonsignificant at 12 months. Conclusions: MI is well accepted by patients suffering from psychosis and has a short-term impact on cannabis use when added to standard care. However, the differential effect was not maintained at 1-year follow-up. MI appears to be a useful active component to reduce cannabis use which should be integrated in routine clinical practice. Copyright (C) 2011 S. Karger AG, Basel
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