期刊
PSYCHONEUROENDOCRINOLOGY
卷 47, 期 -, 页码 26-30出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.psyneuen.2014.04.021
关键词
Cortisol; Hair; Stress; Chronic; Caregiver; Depression; Human
资金
- German Research Foundation (DFG) [KI 537/31-1]
Hair cortisol concentrations (HCC) are assumed to reflect integrated long-term cortisol levels and have been proposed as a promising endocrine marker of chronic psychological stress. The current study examined HCC in relation to caregiving burden, a well-established naturalistic model of chronic stress in humans. HCC and relevant psychosocial data were examined in 20 caregivers of relatives with dementia and 20 non-caregiver controls matched for age and sex. Results revealed elevated HCC in dementia caregivers compared to non-caregiver controls (F-(1,F-38) = 4.4, p = .04, eta(2)(p) = .10). Further, within caregivers, a trend for a positive association of HCC with self-reported caregiving burden (r = .43, p = .058) and a positive association with depressiveness (r = .48, p = .045) were observed. No other associations between HCC and subjective measures were seen. These findings concur with the notion that HCC sensitively capture endocrine aberrations in stress-exposed groups. (C) 2014 Elsevier Ltd. All rights reserved.
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