期刊
BIOINTERPHASES
卷 10, 期 2, 页码 -出版社
AMER INST PHYSICS
DOI: 10.1116/1.4921278
关键词
-
资金
- JSPS KAKENHI [24108004]
- Knowledge based Medical Device Cluster/Miyagi Area
- Grants-in-Aid for Scientific Research [25293074, 26670099, 26600124, 15J01427, 24108004] Funding Source: KAKEN
The cell membrane permeability, which is strongly related to gene transfection, is improved using a cell-solution electrode for generating atmospheric-pressure plasma (APP) just above the solution. In the case of the floating cells, the cell membrane permeability is significantly improved by the cell-solution electrode APP compared with the conventional diffusion type APP, because the distance between the plasma generation area and the cell solution surface becomes short, which could reduce the radial diffusion loss of the plasma irradiated to the cell suspended solution. In the case of the adherent cells, cell membrane permeability is found to be enhanced by the shorter distance between the solution surface and the adherent cells as well as using the cell-solution electrode, which means that the short-lived reactive oxygen species generated at the solution surface are essential for the improvement of cell membrane permeability. (C) 2015 American Vacuum Society.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据