期刊
PSYCHOLOGICAL MEDICINE
卷 49, 期 10, 页码 1691-1704出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0033291718002301
关键词
Major depressive disorder; meta-analysis; suicide attempt
资金
- University of Macau [MYRG2015-00230-FHS, MYRG2016-00005-FHS]
- National Key Research & Development Program of China [2016YFC1307200]
- Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support [ZYLX201607]
- Beijing Municipal Administration of Hospitals' Ascent Plan [DFL20151801]
Background. Suicide attempt (SA), which is one of the strongest predictors of completed suicide, is common in major depressive disorder (MDD) but its prevalence across epidemiological studies has been mixed. The aim of this comprehensive meta-analysis was to examine the pooled prevalence of SA in individuals with MDD. Methods. A systematic literature search was conducted in PubMed, Embase, PsycINFO, Web of Science and Cochrane Library from their commencement date until 27 December 2017. Original studies containing data on prevalence of SA in individuals with MDD were analyzed. Results. In all, 65 studies with a total of 27 340 individuals with MDD were included. Using the random effects model, the pooled lifetime prevalence of SA was 31% [95% confidence interval (CI) 27-34%], 1-year prevalence was 8% (95% CI 3-14%) and 1-month prevalence was 24% (95% CI 15-34%). Subgroup analyses revealed that the lifetime prevalence of SA was significantly associated with the patient setting, study region and income level, while the 1-month prevalence of SA was associated with only the patient setting. Conclusion. This meta-analysis confirmed that SA was common in individuals with MDD across the world. Careful screening and appropriate interventions should be implemented for SA in the MDD population.
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