One-pot synthesis of 1-amidoalkyl-2-naphthols catalyzed by nano-BF3•SiO2

1-Amidoalkyl-2-naphthols were prepared via one-pot multi-component reaction of 2-naphthol, aldehydes, and amides in the presence of nano-silica supported boron trifluoride (nano-BF3 center dot SiO2) in ethyl acetate at 80 degrees C. Short reaction times, high yields, scaleup and easy work-up are the advantages of this protocol. (C) 2015 The Authors. Published by Elsevier B.V. on behalf of King Saud University.