Silent brain infarcts: A cause of depression in the elderly?

The present study included 1047 elderly participants. At baseline, brain magnetic resonance imaging (MRI) was performed to detect infarcts and white matter lesions; further, depressive disorders were assessed. Participants were followed up during 3.6 years to determine incident and recurrent depression. We found an increased risk of recurrent depression associated with silent brain infarcts. (C) 2012 Elsevier Ireland Ltd. All rights reserved.