期刊
PSYCHIATRY RESEARCH
卷 210, 期 3, 页码 951-956出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.psychres.2013.08.057
关键词
Major depressive disorder; Suicide; FSH; Hormone
类别
资金
- National Research Foundation of Korea (NRF)
- Ministry of Education, Science and Technology [2011-0013064]
- Samsung Biomedical Research Institute [C-B1-311]
Current suicidal ideation and attempts are more commonly found in female patients with major depressive disorder (MDD) than in males. However, little is known about the relationship between activity of female reproductive hormones and suicide. The study population consisted of 490 female MDD patients of age >= 18. They were assessed by the Mini-International Neuropsychiatric Interview. At the same visit, we measured blood Follicle-Stimulating Hormone (FSH), Luteinizing Hormone (LH), estradiol, progesterone, Adrenocorticotropic Hormone (ACTH), cortisol, thyroid hormones, and prolactin. Blood FSH showed a significant difference among female MDD patients with suicide attempt, those with ideation, and those without within the previous month. Post-hoc analysis also showed that FSH was significantly lower in MDD patients with suicide attempt and ideation than those without, whereas other hormones showed no differences between those with and without attempt. FSH was negatively associated with current suicidality scores after adjustment for age and education years in all age groups. FSH was significantly lower in those with current suicide ideation or attempt than those without in age 45 years or under, but not in other age groups. In conclusion, blood FSH is significantly lower in female MOD patients with current suicide attempt or ideation than those without, especially in age 45 years or under. (C) 2013 Elsevier Ireland Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据