期刊
PSYCHIATRY RESEARCH
卷 179, 期 2, 页码 238-240出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.psychres.2009.07.017
关键词
Dopamine; DAT gene; Polymorphism; Sleep; SPECT
类别
资金
- Associacao Fundo de Incentivo a Psicofarmacologia (AFIP)
- Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (CEPID) [98/14303-3]
- Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)
- Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [98/14303-3] Funding Source: FAPESP
Genetic variants may modulate dopamine transporter (DAT) availability in the brain. A polymorphism within the intron 8 of the DAT1 gene was evaluated in 27 healthy men. No correlation between Int8 VNTR and either the inter-individual variability of the sleep architecture, or the DAT availability, as measured by single photon emission computed tomography (SPECT) and [Tc-99m]TRODAT-1 was observed. (C) 2009 Elsevier Ireland Ltd. All rights reserved.
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