4.4 Article

What generates flux of tubulin in kinetochore microtubules?

期刊

PROTOPLASMA
卷 232, 期 3-4, 页码 137-141

出版社

SPRINGER WIEN
DOI: 10.1007/s00709-008-0286-y

关键词

mitotic spindle; spindle matrix; microtubule dynamics; actin; myosin

向作者/读者索取更多资源

We discuss models for production of tubulin flux in kinetochore microtubules. Current models concentrate solely on microtubules and their associated motors and enzymes. For example, in some models the driving force for flux is enzymes at the poles and the kinetochores; in others the driving force is motor molecules that are associated with a stationary spindle matrix. We present a different viewpoint, that microtubules are propelled poleward by forces arising from the spindle matrix, that the forces on the microtubules activate polymerising and depolymerising enzymes at kinetochores and poles, that matrix forces utilise actin, myosin, and microtubule motors, and that the matrix itself may not necessarily be static.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.4
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据