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Cathepsin H Mediates the Processing of Talin and Regulates Migration of Prostate Cancer Cells
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EMBO JOURNAL (2012)
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NUCLEIC ACIDS RESEARCH (2012)
Cathepsin X in serum from patients with colorectal cancer: relation to prognosis
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RADIOLOGY AND ONCOLOGY (2012)
Functional protease profiling for diagnosis of malignant disease
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PROTEOMICS CLINICAL APPLICATIONS (2012)
Functional in vivo imaging of cysteine cathepsin activity in murine model of inflammation
Dejan Caglic et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2011)
Cathepsin-L contributes to cardiac repair and remodelling post-infarction
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CARDIOVASCULAR RESEARCH (2011)
Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer
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GENES & DEVELOPMENT (2011)
Proteomic Identification of Protease Cleavage Sites Characterizes Prime and Non-prime Specificity of Cysteine Cathepsins B, L, and S
Martin L. Biniossek et al.
JOURNAL OF PROTEOME RESEARCH (2011)
Cathepsin b: a potential prognostic marker for inflammatory breast cancer
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JOURNAL OF TRANSLATIONAL MEDICINE (2011)
Ferri-liposomes as an MRI-visible drug-delivery system for targeting tumours and their microenvironment
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NATURE NANOTECHNOLOGY (2011)
Proteolytic networks in cancer
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TRENDS IN CELL BIOLOGY (2011)
Structural basis for the recognition and cleavage of histone H3 by cathepsin L
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Elevated Cyclic Stretch Induces Aortic Valve Calcification in a Bone Morphogenic Protein-Dependent Manner
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AMERICAN JOURNAL OF PATHOLOGY (2010)
Cathepsins B and L in peripheral blood mononuclear cells of pediatric acute myeloid leukemia: potential poor prognostic markers
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ANNALS OF HEMATOLOGY (2010)
Nuclear cysteine cathepsin variants in thyroid carcinoma cells
Sofia Tedelind et al.
BIOLOGICAL CHEMISTRY (2010)
Expression and activity profiling of selected cysteine cathepsins and matrix metalloproteinases in synovial fluids from patients with rheumatoid arthritis and osteoarthritis
Urska Pozgan et al.
BIOLOGICAL CHEMISTRY (2010)
Stefin B Interacts with Histones and Cathepsin L in the Nucleus
Slavko Ceru et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Pharmacological Inhibition of Cathepsin S Decreases Atherosclerotic Lesions in Apoe-/- Mice
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JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2010)
Specialized roles for cysteine cathepsins in health and disease
Jochen Reiser et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Emerging principles in protease-based drug discovery
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NATURE REVIEWS DRUG DISCOVERY (2010)
Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice
Lisa Sevenich et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Usefulness of Serum Cathepsin L as an Independent Biomarker in Patients With Coronary Heart Disease
Yingxian Liu et al.
AMERICAN JOURNAL OF CARDIOLOGY (2009)
Elevated cyclic stretch alters matrix remodeling in aortic valve cusps: implications for degenerative aortic valve disease
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AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2009)
Arterial and Aortic Valve Calcification Abolished by Elastolytic Cathepsin S Deficiency in Chronic Renal Disease
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CIRCULATION (2009)
Cystatin C and NT-proBNP, a powerful combination of biomarkers for predicting cardiovascular mortality in elderly patients with heart failure: results from a 10-year study in primary care
Urban Alehagen et al.
EUROPEAN JOURNAL OF HEART FAILURE (2009)
Lysosomal cysteine peptidase cathepsin L protects against cardiac hypertrophy through blocking AKT/GSK3β signaling
Qizhu Tang et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2009)
Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function
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NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
Histone H3 tail clipping regulates gene expression
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NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
Superoxide-dependent cathepsin activation is associated with hypertensive myocardial remodeling and represents a target for angiotensin II type 1 receptor blocker treatment
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AMERICAN JOURNAL OF PATHOLOGY (2008)
Selective activity-based probes for cysteine cathepsins
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ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2008)
Dual contrasting roles of cysteine cathepsins in cancer progression: Apoptosis versus tumour invasion
Olga Vasiljeva et al.
BIOCHIMIE (2008)
Cathepsin L Proteolytically Processes Histone H3 During Mouse Embryonic Stem Cell Differentiation
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CELL (2008)
Application of activity-based probes to the study of enzymes involved in cancer progression
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CURRENT OPINION IN GENETICS & DEVELOPMENT (2008)
Cysteine protease cathepsin X modulates immune response via activation of β2 integrins
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IMMUNOLOGY (2008)
Nuclear Cathepsin F Regulates Activation Markers in Rat Hepatic Stellate Cells
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MOLECULAR BIOLOGY OF THE CELL (2008)
Reduced tumour cell proliferation and delayed development of high-grade mammary carcinomas in cathepsin B-deficient mice
O. Vasiljeva et al.
ONCOGENE (2008)
Cathepsin B, K, and S are expressed in cerebral aneurysms and promote the progression of cerebral aneurysms
Tomohiro Aoki et al.
STROKE (2008)
Cysteine cathepsin proteases as pharmacological targets in cancer
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TRENDS IN PHARMACOLOGICAL SCIENCES (2008)
Reappraising metalloproteinases in rheumatoid arthritis and osteoarthritis: destruction or repair?
Gillian Murphy et al.
NATURE CLINICAL PRACTICE RHEUMATOLOGY (2008)
Angiotensin inhibition decreases progression of advanced atherosclerosis and stabilizes established atherosclerotic plaques
Eisuke Suganuma et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2007)
Proteomic discovery of protease substrates
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CURRENT OPINION IN CHEMICAL BIOLOGY (2007)
Emerging roles of cysteine cathepsins in disease and their potential as drug targets
Olga Vasiljeva et al.
CURRENT PHARMACEUTICAL DESIGN (2007)
Activity based probes for proteases: Applications to biomarker discovery, molecular imaging and drug screening
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CURRENT PHARMACEUTICAL DESIGN (2007)
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CELL CYCLE (2007)
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NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Elastolytic cathepsin induction/activation system exists in myocardium and is upregulated in hypertensive heart failure
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HYPERTENSION (2006)
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Increased expression of elastolytic cathepsins S, K, and V and their inhibitor cystatin C in stenotic aortic valves
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ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2006)
Significance of 32-kDa cathepsin L secreted from cancer cells
Yoko Hashimoto et al.
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2006)
Increased serum cathepsin S in patients with atherosclerosis and diabetes
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ATHEROSCLEROSIS (2006)
Lysosomal, cytoskeletal, and metabolic alterations in cardiomyopathy of cathepsin L knockout mice
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FASEB JOURNAL (2006)
Tumor cell-derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer
Olga Vasiljeva et al.
CANCER RESEARCH (2006)
Inflammation and cellular immune responses in abdominal aortic aneurysms
K Shimizu et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2006)
Destabilizing role of cathepsin S in murine atherosclerotic plaques
KJ Rodgers et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2006)
Distinct roles for cysteine cathepsin genes in multistage tumorigenesis
V Gocheva et al.
GENES & DEVELOPMENT (2006)
Cathepsin L expression and regulation in human abdominal aortic aneurysm, atherosclerosis, and vascular cells
J Liu et al.
ATHEROSCLEROSIS (2006)
Localization of cysteine protease, cathepsin S, to the surface of vascular smooth muscle cells by association with integrin ανβ3
XW Cheng et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
Disruption of the Cathepsin K gene reduces atherosclerosis progression and induces plaque fibrosis but accelerates macrophage foam cell formation
E Lutgens et al.
CIRCULATION (2006)
Targeting proteases: successes, failures and future prospects
Boris Turk
NATURE REVIEWS DRUG DISCOVERY (2006)
Caspase-specific and nonspecific in vivo protein processing during Fas-induced apoptosis
P Van Damme et al.
NATURE METHODS (2005)
Cathepsin L is required for endothelial progenitor cell-induced neovascularization
C Urbich et al.
NATURE MEDICINE (2005)
Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis
JA Joyce et al.
CANCER CELL (2004)
A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor
B Goulet et al.
MOLECULAR CELL (2004)
Cysteine proteases as disease markers
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CLINICA CHIMICA ACTA (2004)
Early diagnosis of osteoarthritis using cathepsin B sensitive near-infrared fluorescent probes
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OSTEOARTHRITIS AND CARTILAGE (2004)
HaCaT keratinocytes secrete lysosomal cysteine proteinases during migration
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EUROPEAN JOURNAL OF CELL BIOLOGY (2004)
Inhibition of tumorigenicity and metastasis of human melanoma cells by anti-cathepsin L single chain variable fragment
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CANCER RESEARCH (2004)
Mutant K-ras regulates cathepsin B localization on the surface of human colorectal carcinoma cells
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NEOPLASIA (2003)
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NATURE REVIEWS CANCER (2003)
The clinical significance of cathepsin S expression in human astrocytomas
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AMERICAN JOURNAL OF PATHOLOGY (2003)
Cleavage site specificity of cathepsin K toward cartilage proteoglycans and protease complex formation
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BIOLOGICAL CHEMISTRY (2003)
Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides
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NATURE BIOTECHNOLOGY (2003)
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NATURE REVIEWS CANCER (2002)
Degradation of extracellular matrix protein tenascin-C by cathepsin B: An interaction involved in the progression of gliomas
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BIOLOGICAL CHEMISTRY (2002)
Differential expression of cysteine and aspartic proteases during progression of atherosclerosis in apolipoprotein E-deficient mice
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AMERICAN JOURNAL OF PATHOLOGY (2002)
Dilated cardiomyopathy in mice deficient for the lysosomal cysteine peptidase cathepsin L
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Acidic cysteine endoproteinase cathepsin K in the degeneration of the superficial articular hyaline cartilage in osteoarthritis
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ARTHRITIS AND RHEUMATISM (2002)
Cancer therapy - Matrix metalloproteinase inhibitors and cancer: Trials and tribulations
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SCIENCE (2002)
Analysis of a truncated form of cathepsin H in human prostate tumor cells
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JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Regulating cysteine protease activity: Essential role of protease inhibitors as guardians and regulators
B Turk et al.
CURRENT PHARMACEUTICAL DESIGN (2002)
Comparison of cathepsins K and S expression within the rheumatoid and osteoarthritic synovium
WS Hou et al.
ARTHRITIS AND RHEUMATISM (2002)
Cathepsin K is a critical protease in synovial fibroblast-mediated collagen degradation
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AMERICAN JOURNAL OF PATHOLOGY (2001)
Cathepsin S in tumours, regional lymph nodes and sera of patients with lung cancer: relation to prognosis
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BRITISH JOURNAL OF CANCER (2001)
Biosynthesis and processing of cathepsin K in cultured human osteoclasts
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