期刊
PROTEOMICS
卷 11, 期 15, 页码 3244-3255出版社
WILEY
DOI: 10.1002/pmic.201000786
关键词
Corynebacterium diphtheriae; Corynebacterium glutamicum; Microbiology; Mycobacterium
Corynebacteria belong to the high G+C Gram-positive bacteria (Actinobacteria) and are closely related to Mycobacterium and Nocardia species. The best investigated member of this group of almost seventy species is Corynebacterium glutamicum, a soil bacterium isolated in 1957, which is used for the industrial production of more than two million tons of amino acids per year. This review focuses on the technical advances made in proteomics approaches during the last years and summarizes applications of these techniques with respect to C. glutamicum metabolic pathways and stress response. Additionally, selected proteome applications for other biotechnologically important or pathogenic corynebacteria are described.
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