相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Proof of principle for epitope-focused vaccine design
Bruno E. Correia et al.
NATURE (2014)
Identification of autoantigens recognized by the 2F5 and 4E10 broadly neutralizing HIV-1 antibodies
Guang Yang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
A comparison of successful and failed protein interface designs highlights the challenges of designing buried hydrogen bonds
P. Benjamin Stranges et al.
PROTEIN SCIENCE (2013)
Advances in structure-based vaccine design
Daniel W. Kulp et al.
CURRENT OPINION IN VIROLOGY (2013)
Structural insights for engineering binding proteins based on non-antibody scaffolds
Ryan N. Gilbreth et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2012)
Comparison of two measuring instruments, B-pro and SphygmoCor system as reference, to evaluate central systolic blood pressure and radial augmentation index
Luis Garcia-Ortiz et al.
HYPERTENSION RESEARCH (2012)
Computational Design of High-Affinity Epitope Scaffolds by Backbone Grafting of a Linear Epitope
Mihai L. Azoitei et al.
JOURNAL OF MOLECULAR BIOLOGY (2012)
Increased Antibody Affinity Confers Broad In Vitro Protection against Escape Mutants of Severe Acute Respiratory Syndrome Coronavirus
Mridula Rani et al.
JOURNAL OF VIROLOGY (2012)
HIV-1 Neutralizing Antibodies Display Dual Recognition of the Primary and Coreceptor Binding Sites and Preferential Binding to Fully Cleaved Envelope Glycoproteins
Yuxing Li et al.
JOURNAL OF VIROLOGY (2012)
Broad and potent neutralization of HIV-1 by a gp41-specific human antibody
Jinghe Huang et al.
NATURE (2012)
Structure-guided Alterations of the gp41-directed HIV-1 Broadly Neutralizing Antibody 2F5 Reveal New Properties Regarding its Neutralizing Function
Javier Guenaga et al.
PLOS PATHOGENS (2012)
Design and Characterization of Epitope-Scaffold Immunogens That Present the Motavizumab Epitope from Respiratory Syncytial Virus
Jason S. McLellan et al.
JOURNAL OF MOLECULAR BIOLOGY (2011)
Antibody mechanics on a membrane-bound HIV segment essential for GP41-targeted viral neutralization
Mikyung Kim et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)
Heterologous Epitope-Scaffold Prime:Boosting Immuno-Focuses B Cell Responses to the HIV-1 gp41 2F5 Neutralization Determinant
Javier Guenaga et al.
PLOS ONE (2011)
Anchored Design of Protein-Protein Interfaces
Steven M. Lewis et al.
PLOS ONE (2011)
Computation-Guided Backbone Grafting of a Discontinuous Motif onto a Protein Scaffold
Mihai L. Azoitei et al.
SCIENCE (2011)
Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin
Sarel J. Fleishman et al.
SCIENCE (2011)
Computational Design of a PAK1 Binding Protein
Ramesh K. Jha et al.
JOURNAL OF MOLECULAR BIOLOGY (2010)
Relationship between Antibody 2F5 Neutralization of HIV-1 and Hydrophobicity of Its Heavy Chain Third Complementarity-Determining Region
Gilad Ofek et al.
JOURNAL OF VIROLOGY (2010)
Ablation of the Complementarity-Determining Region H3 Apex of the Anti-HIV-1 Broadly Neutralizing Antibody 2F5 Abrogates Neutralizing Capacity without Affecting Core Epitope Binding
Jean-Philippe Julien et al.
JOURNAL OF VIROLOGY (2010)
Elicitation of structure-specific antibodies by epitope scaffolds
Gilad Ofek et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope
Bruno E. Correia et al.
STRUCTURE (2010)
Backbone flexibility in computational protein design
Daniel J. Mandell et al.
CURRENT OPINION IN BIOTECHNOLOGY (2009)
Computational design of affinity and specificity at protein-protein interfaces
John Karanicolas et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2009)
Role of HIV membrane in neutralization by two broadly neutralizing antibodies
S. Munir Alam et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Macromolecular modeling with Rosetta
Rhiju Das et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2008)
Picomolar affinity fibronectin domains engineered utilizing loop length diversity, recursive mutagenesis, and loop shuffling
Benjamin J. Hackel et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
Structural Details of HIV-1 Recognition by the Broadly Neutralizing Monoclonal Antibody 2F5: Epitope Conformation, Antigen-Recognition Loop Mobility, and Anion-Binding Site
Jean-Philippe Julien et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
Inference of macromolecular assemblies from crystalline state
Evgeny Krissinel et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
Crystal structure of isoflavone reductase from alfalfa (Medicago sativa L.)
Xiaoqiang Wang et al.
JOURNAL OF MOLECULAR BIOLOGY (2006)
Isolating and engineering human antibodies using yeast surface display
Ginger Chao et al.
NATURE PROTOCOLS (2006)
Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope
G Ofek et al.
JOURNAL OF VIROLOGY (2004)
Protein-protein docking with simultaneous optimization of rigid-body displacement and side-chain conformations
JJ Gray et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)
Structure of ribosomal protein L1 from Methanococcus thermolithotrophicus.: Functionally important structural invariants on the L1 surface
N Nevskaya et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2002)
Crystal structure of hyaluronidase, a major allergen of bee venom
Z Markovic-Housley et al.
STRUCTURE (2000)
Unexpected structural diversity in DNA recombination: The restriction endonuclease connection
AB Hickman et al.
MOLECULAR CELL (2000)
The Protein Data Bank
HM Berman et al.
NUCLEIC ACIDS RESEARCH (2000)