4.1 Article

Transfer of engineered biophysical properties between different antibody formats and expression systems

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biotechnology & Applied Microbiology

Comprehensive engineering of Escherichia coli for enhanced expression of IgG antibodies

Tomohiro Makino et al.

METABOLIC ENGINEERING (2011)

Article Chemistry, Medicinal

An Industry Perspective on the Monitoring of Subvisible Particles as a Quality Attribute for Protein Therapeutics

Satish K. Singh et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2010)

Review Immunology

Complement: a key system for immune surveillance and homeostasis

Daniel Ricklin et al.

NATURE IMMUNOLOGY (2010)

Review Biochemistry & Molecular Biology

How antibodies fold

Matthias J. Feige et al.

TRENDS IN BIOCHEMICAL SCIENCES (2010)

Article Multidisciplinary Sciences

Protein-binding assays in biological liquids using microscale thermophoresis

Christoph J. Wienken et al.

NATURE COMMUNICATIONS (2010)

Article Immunology

Strategies and challenges for the next generation of therapeutic antibodies

Alain Beck et al.

NATURE REVIEWS IMMUNOLOGY (2010)

Review Biochemical Research Methods

Optimization of Fc-mediated effector functions of monoclonal antibodies

William R. Strohl

CURRENT OPINION IN BIOTECHNOLOGY (2009)

Article Biochemistry & Molecular Biology

Conserved amino acid networks involved in antibody variable domain interactions

Norman Wang et al.

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2009)

Review Pharmacology & Pharmacy

Recombinant antibody therapeutics: the impact of glycosylation on mechanisms of action

Royston Jefferis

TRENDS IN PHARMACOLOGICAL SCIENCES (2009)

Article Biochemical Research Methods

Microchip assays for screening monoclonal antibody product quality

Xiaoyu Chen et al.

ELECTROPHORESIS (2008)

Review Biochemistry & Molecular Biology

Protein quality control in the early secretory pathway

Tiziana Anelli et al.

EMBO JOURNAL (2008)

Article Biochemistry & Molecular Biology

Human IgG2 antibodies display disulfide-mediated structural isoforms

Jette Wypych et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Chemistry, Medicinal

Contribution of variable domains to the stability of humanized IgG1 monoclonal antibodies

Roxana M. Ionescu et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2008)

Article Biotechnology & Applied Microbiology

Characterization of lower molecular weight artifact bands of recombinant monoclonal IgG1 antibodies on non-reducing SDS-PAGE

Hongcheng Liu et al.

BIOTECHNOLOGY LETTERS (2007)

Article Biochemistry & Molecular Biology

A broad range of Fab stabilities within a host of therapeutic IgGs

Ellen Garber et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)

Article Biochemistry & Molecular Biology

A role for protein misfolding in immunogenicity of biopharmaceuticals

Coen Maas et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemical Research Methods

The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability

Frank H. Niesen et al.

NATURE PROTOCOLS (2007)

Review Immunology

FcRn: the neonatal Fc receptor comes of age

Derry C. Roopenian et al.

NATURE REVIEWS IMMUNOLOGY (2007)

Article Biochemistry & Molecular Biology

Improving the stability of an antibody variable fragment by a combination of knowledge-based approaches: Validation and mechanisms

Elodie Monsellier et al.

JOURNAL OF MOLECULAR BIOLOGY (2006)

Article Biochemistry & Molecular Biology

Engineering stability into Escherichia coli secreted Fabs leads to increased functional expression

Stephen J. Demarest et al.

PROTEIN ENGINEERING DESIGN & SELECTION (2006)

Article Multidisciplinary Sciences

Engineered antibody Fc variants with enhanced effector function

GA Lazar et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Review Multidisciplinary Sciences

Protein folding and misfolding

CM Dobson

NATURE (2003)

Article Biotechnology & Applied Microbiology

Turnover-based in vitro selection and evolution of biocatalysts from a fully synthetic antibody library

S Cesaro-Tadic et al.

NATURE BIOTECHNOLOGY (2003)

Article Biochemistry & Molecular Biology

Biophysical properties of human antibody variable domains

S Ewert et al.

JOURNAL OF MOLECULAR BIOLOGY (2003)

Article Biotechnology & Applied Microbiology

Free sulfhydryl in recombinant monoclonal antibodies

W Zhang et al.

BIOTECHNOLOGY PROGRESS (2002)

Article Biochemical Research Methods

Expression of full-length immunoglobulins in Escherichia coli:: rapid and efficient production of aglycosylated antibodies

LC Simmons et al.

JOURNAL OF IMMUNOLOGICAL METHODS (2002)

Article Biochemistry & Molecular Biology

Biophysical properties of camelid VHH domains compared to those of human VH3 domains

S Ewert et al.

BIOCHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Yet another numbering scheme for immunoglobulin variable domains:: An automatic modeling and analysis tool

A Honegger et al.

JOURNAL OF MOLECULAR BIOLOGY (2001)

Review Biochemistry & Molecular Biology

Stability engineering of antibody single-chain Fv fragments

A Wörn et al.

JOURNAL OF MOLECULAR BIOLOGY (2001)