4.2 Article

Prediction of G-Protein-Coupled Receptor Classes in Low Homology Using Chou's Pseudo Amino Acid Composition with Approximate Entropy and Hydrophobicity Patterns

期刊

PROTEIN AND PEPTIDE LETTERS
卷 17, 期 5, 页码 559-567

出版社

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/092986610791112693

关键词

G-protein-coupled receptors; low homology; pseudo amino acid; approximate entropy; hydrophobicity patterns; AdaBoost

资金

  1. National Nature Science Foundation of China [60975059]
  2. Ministry of Education of China [20090075110002]
  3. Shanghai Committee of Science and Technology [08JC1400100]
  4. Key Laboratory of MICCAI of Shanghai [06dz22103]

向作者/读者索取更多资源

We use approximate entropy and hydrophobicity patterns to predict G-protein-coupled receptors. Adaboost classifier is adopted as the prediction engine. A low homology dataset is used to validate the proposed method. Compared with the results reported, the successful rate is encouraging. The source code is written by Matlab.

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