期刊
ACS COMBINATORIAL SCIENCE
卷 17, 期 2, 页码 81-86出版社
AMER CHEMICAL SOC
DOI: 10.1021/co500176b
关键词
olefin metathesis; solid-phase organic synthesis; chalcones; beta-phenylpropiophenone derivatives; microwave heating
资金
- CONICET
- ANPCyT
- Universidad Nacional de Rosario from Argentina
Solid-phase synthetic strategies toward the generation of libraries of biologically relevant molecules were developed using olefin cross-metathesis as a key step. It is remarkably the formal alkane metathesis based on a one-pot, microwave-assisted, ruthenium-catalyzed cross-metathesis and reduction to obtain Csp3-Csp3 linkages.
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