期刊
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
卷 86, 期 4-5, 页码 183-188出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.plefa.2012.02.008
关键词
Arachidonic acid; Bayley's Scales; Docosahexaenoic acid; General movements; Linoleic acid; Mead acid
资金
- SAS, Boras
- Vastra Gotaland Research and Development
- Royal Society of Sciences and Arts in Gothenburg
The objective of this study was to investigate any association between infants' early development and PUFA concentrations in early breast milk and infants' plasma phospholipids at 44 weeks gestational age. Fifty-one premature infants were included. The quality of general movement was assessed at 3 months, and motor, mental and behavioral development at 3, 6, 10 and 18 months corrected age using Bayley's Scales of Infant Development (BSID-II). Linoleic acid, the major n-6/n-3 FA ratios, Mead acid and the EFA deficiency index in early breast milk were negatively associated with development up to 18 months of age. DHA and AA, respectively, in infants' plasma phospholipids was positively, but the AA/DHA ratio negatively, associated with development from 6 to 18 months of age. Our data suggest that the commonly found high n-6 concentration in breast milk is associated with less favorable motor, mental and behavioral development up to 18 months of age. (C) 2012 Published by Elsevier Ltd.
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