期刊
PROGRESS IN LIPID RESEARCH
卷 48, 期 3-4, 页码 148-170出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.plipres.2009.02.002
关键词
CYP74; Dioxygenases; Eicosanoids; Jasmonates; Lipid peroxidation; Lipoxygenases; Metabolic pathways; Octadecanoids
资金
- German Research Foundation
- European Commission and Frimenich SA, Geneva
- International Master/Ph.D. programme Molecular Biology (Goettingen)
- International Research Training Group [1422]
Lipid peroxidation is common to all biological systems, appearing in developmentally-regulated processes and as a response to environmental changes. Products derived from lipid peroxidation are collectively named oxylipins. Initial lipid peroxidation may either occur by enzymatic or chemical reactions. An array of alternative reactions further converting lipid hydroperoxides gives rise to a large variety of oxylipin classes, some with reported signaling functions in plants, fungi, algae or animals. The structural diversity of oxylipins is further increased by their occurrence either as esters in complex lipids or as free (non-esterified) fatty acid derivatives. The enzymes involved in oxylipin metabolism are diverse and comprise a multitude of examples with interesting and unusual catalytic properties. This review aims at giving an overview on plant, fungal, algal and bacterial oxylipins and the enzymes responsible for their biosynthesis. (C) 2009 Elsevier Ltd. All rights reserved.
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